The ERRα–VDR axis promotes calcitriol degradation and estrogen signaling in breast cancer cells, while VDR‐CYP24A1‐ERRα overexpression correlates with poor prognosis in patients with basal‐like breast cancer

Vitamin D is used to reduce cancer risk and improve the outcome of cancer patients, but the vitamin D receptor (VDR; also known as the calcitriol receptor) pathway needs to be functionally intact to ensure the biological effects of circulating calcitriol, the active form of vitamin D. Besides estrog...

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Detalles Bibliográficos
Autores principales: Danza, Katia, Porcelli, Letizia, De Summa, Simona, Di Fonte, Roberta, Pilato, Brunella, Lacalamita, Rosanna, Serratì, Simona, Azzariti, Amalia, Tommasi, Stefania
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8847991/
https://www.ncbi.nlm.nih.gov/pubmed/34003583
http://dx.doi.org/10.1002/1878-0261.13013

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