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Antibody structure prediction using interpretable deep learning

Therapeutic antibodies make up a rapidly growing segment of the biologics market. However, rational design of antibodies is hindered by reliance on experimental methods for determining antibody structures. Here, we present DeepAb, a deep learning method for predicting accurate antibody F(V) structur...

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Detalles Bibliográficos
Autores principales:	Ruffolo, Jeffrey A., Sulam, Jeremias, Gray, Jeffrey J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8848015/ https://www.ncbi.nlm.nih.gov/pubmed/35199061 http://dx.doi.org/10.1016/j.patter.2021.100406

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