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Ginseng for the Treatment of Chronic Fatigue Syndrome: A Systematic Review of Clinical Studies
BACKGROUND: Chronic fatigue syndrome (CFS) is a complex and often disabling chronic condition emerging worldwide, with no curative or definitive therapy yet identified. Ginseng has been widely used to treat fatigue in other patient groups and conditions; however, a systematic review focusing solely...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8848096/ https://www.ncbi.nlm.nih.gov/pubmed/35186446 http://dx.doi.org/10.1177/2164957X221079790 |
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author | Yang, Juan Shin, Kyung-Min Abu Dabrh, Abd Moain Bierle, Dennis M Zhou, Xuan Bauer, Brent A. Mohabbat, Arya B |
author_facet | Yang, Juan Shin, Kyung-Min Abu Dabrh, Abd Moain Bierle, Dennis M Zhou, Xuan Bauer, Brent A. Mohabbat, Arya B |
author_sort | Yang, Juan |
collection | PubMed |
description | BACKGROUND: Chronic fatigue syndrome (CFS) is a complex and often disabling chronic condition emerging worldwide, with no curative or definitive therapy yet identified. Ginseng has been widely used to treat fatigue in other patient groups and conditions; however, a systematic review focusing solely on the impact of ginseng on fatigue in patients with CFS has not been performed. OBJECTIVE: This study aimed to assess the current state of evidence regarding ginseng for CFS. METHODS: Multiple databases were searched from inception to October 2020. All data was extracted independently and in duplicates. Outcomes of interest included the effectiveness and safety of ginseng in patients with CFS. RESULTS: 2 studies enrolling 68 patients were deemed eligible, including one randomized clinical trial and one prospective observational study. The certainty of evidence in the effectiveness outcome was low and moderate from both studies, while the safety evidence was very low as reported from one study. CONCLUSION: Study findings highlight a potential benefit of ginseng therapy in the treatment of CFS. However, we are not able to draw firm conclusions due to limited clinical studies. The paucity of data warrants limited confidence. There is a need for future rigorous studies to provide further evidence. |
format | Online Article Text |
id | pubmed-8848096 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | SAGE Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-88480962022-02-17 Ginseng for the Treatment of Chronic Fatigue Syndrome: A Systematic Review of Clinical Studies Yang, Juan Shin, Kyung-Min Abu Dabrh, Abd Moain Bierle, Dennis M Zhou, Xuan Bauer, Brent A. Mohabbat, Arya B Glob Adv Health Med Systematic Review and Meta-analyses BACKGROUND: Chronic fatigue syndrome (CFS) is a complex and often disabling chronic condition emerging worldwide, with no curative or definitive therapy yet identified. Ginseng has been widely used to treat fatigue in other patient groups and conditions; however, a systematic review focusing solely on the impact of ginseng on fatigue in patients with CFS has not been performed. OBJECTIVE: This study aimed to assess the current state of evidence regarding ginseng for CFS. METHODS: Multiple databases were searched from inception to October 2020. All data was extracted independently and in duplicates. Outcomes of interest included the effectiveness and safety of ginseng in patients with CFS. RESULTS: 2 studies enrolling 68 patients were deemed eligible, including one randomized clinical trial and one prospective observational study. The certainty of evidence in the effectiveness outcome was low and moderate from both studies, while the safety evidence was very low as reported from one study. CONCLUSION: Study findings highlight a potential benefit of ginseng therapy in the treatment of CFS. However, we are not able to draw firm conclusions due to limited clinical studies. The paucity of data warrants limited confidence. There is a need for future rigorous studies to provide further evidence. SAGE Publications 2022-02-14 /pmc/articles/PMC8848096/ /pubmed/35186446 http://dx.doi.org/10.1177/2164957X221079790 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage). |
spellingShingle | Systematic Review and Meta-analyses Yang, Juan Shin, Kyung-Min Abu Dabrh, Abd Moain Bierle, Dennis M Zhou, Xuan Bauer, Brent A. Mohabbat, Arya B Ginseng for the Treatment of Chronic Fatigue Syndrome: A Systematic Review of Clinical Studies |
title | Ginseng for the Treatment of Chronic Fatigue Syndrome: A Systematic Review of Clinical Studies |
title_full | Ginseng for the Treatment of Chronic Fatigue Syndrome: A Systematic Review of Clinical Studies |
title_fullStr | Ginseng for the Treatment of Chronic Fatigue Syndrome: A Systematic Review of Clinical Studies |
title_full_unstemmed | Ginseng for the Treatment of Chronic Fatigue Syndrome: A Systematic Review of Clinical Studies |
title_short | Ginseng for the Treatment of Chronic Fatigue Syndrome: A Systematic Review of Clinical Studies |
title_sort | ginseng for the treatment of chronic fatigue syndrome: a systematic review of clinical studies |
topic | Systematic Review and Meta-analyses |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8848096/ https://www.ncbi.nlm.nih.gov/pubmed/35186446 http://dx.doi.org/10.1177/2164957X221079790 |
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