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In-silico study of seaweed secondary metabolites as AXL kinase inhibitors

AXL kinase is an attractive cancer target for drug design and it is involved in different cancers. A set of molecule databases with 1072 secondary metabolites from seaweeds were screened against the AXL kinase active site and eight molecules were shortlisted for further studies. From the docking ana...

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Detalles Bibliográficos
Autores principales: Nagamalla, Lavanya, Shanmukha Kumar, J.V., Sanjay, Chintakindi, Alsamhan, Ali M, Shaik, Mohammed Rafi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8848138/
https://www.ncbi.nlm.nih.gov/pubmed/35197734
http://dx.doi.org/10.1016/j.sjbs.2021.11.054