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Matrine exerts antitumor activity in cervical cancer by protective autophagy via the Akt/mTOR pathway in vitro and in vivo

Matrine is a quinazoline alkaloid extracted from Sophora flavescens. The aim of the present study was to determine whether matrine can induce autophagy in the human HeLa and SiHa cervical cancer cell lines in vitro and in vivo. Cell viability assay was used to assess the suppressive effect of matrin...

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Detalles Bibliográficos
Autores principales: Zhang, Fan, Zhang, Hua, Qian, Wenjun, Xi, Yuyan, Chang, Lihua, Wu, Xiaoling, Li, Mu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8848215/
https://www.ncbi.nlm.nih.gov/pubmed/35242238
http://dx.doi.org/10.3892/ol.2022.13230