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Matrine exerts antitumor activity in cervical cancer by protective autophagy via the Akt/mTOR pathway in vitro and in vivo
Matrine is a quinazoline alkaloid extracted from Sophora flavescens. The aim of the present study was to determine whether matrine can induce autophagy in the human HeLa and SiHa cervical cancer cell lines in vitro and in vivo. Cell viability assay was used to assess the suppressive effect of matrin...
Autores principales: | Zhang, Fan, Zhang, Hua, Qian, Wenjun, Xi, Yuyan, Chang, Lihua, Wu, Xiaoling, Li, Mu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8848215/ https://www.ncbi.nlm.nih.gov/pubmed/35242238 http://dx.doi.org/10.3892/ol.2022.13230 |
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