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Bimalleolar pathological fracture in a patient with chronic tophaceous gout

Gout is one of the most common types of inflammatory arthritis. Four stages have been described in its evolution: asymptomatic hyperuricemia, acute gouty arthritis, intercritical gout and chronic tophaceous gout. Monosodium urate crystals deposits are more frequently encountered in hyaline cartilage...

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Autores principales: Irsay, László, Perja, Dănuţ-Georgel, Kamal, Kamal Constantin, Trăistaru, Magdalena Rodica, Kamal, Diana, Ciortea, Viorela Mihaela, Popa, Theodor, Borda, Ileana Monica, Ungur, Rodica Ana, Ciubean, Alina Deniza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academy of Medical Sciences, Romanian Academy Publishing House, Bucharest 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8848262/
https://www.ncbi.nlm.nih.gov/pubmed/35024751
http://dx.doi.org/10.47162/RJME.62.2.29
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author Irsay, László
Perja, Dănuţ-Georgel
Kamal, Kamal Constantin
Trăistaru, Magdalena Rodica
Kamal, Diana
Ciortea, Viorela Mihaela
Popa, Theodor
Borda, Ileana Monica
Ungur, Rodica Ana
Ciubean, Alina Deniza
author_facet Irsay, László
Perja, Dănuţ-Georgel
Kamal, Kamal Constantin
Trăistaru, Magdalena Rodica
Kamal, Diana
Ciortea, Viorela Mihaela
Popa, Theodor
Borda, Ileana Monica
Ungur, Rodica Ana
Ciubean, Alina Deniza
author_sort Irsay, László
collection PubMed
description Gout is one of the most common types of inflammatory arthritis. Four stages have been described in its evolution: asymptomatic hyperuricemia, acute gouty arthritis, intercritical gout and chronic tophaceous gout. Monosodium urate crystals deposits are more frequently encountered in hyaline cartilage, tendon sheaths, articular bursae, bone epiphysis, synovium, and skin. Pathological fractures that occur at the formation sites of gout tophi have been rarely described in gout. Bimalleolar fractures often occur following a trauma. We present the case of a 56-year-old patient, diagnosed with chronic gout for over 12 years, with tophi in the upper and lower limbs, who presented accusing mechanical pain in the left tibio-tarsal joint and impaired function of the hands. The clinical examination showed bilateral multiple destructive gout tophi in the hands, forearms, elbows, feet, ankles, and lower legs, while the left ankle exhibited an important varus deformity. Computed tomography examination of the left ankle showed multiple gout tophi with bone erosions and a bimalleolar pathological fracture. The patient underwent pharmacological treatment, physical therapy and the ankle was immobilized in a knee-ankle-foot orthosis, with subsequent orthopedic surgical treatment for fracture fixation, to improve functional status. We have chosen to present this case given the multiple disabilities of the patient, which have improved following the rehabilitation treatment.
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spelling pubmed-88482622022-03-07 Bimalleolar pathological fracture in a patient with chronic tophaceous gout Irsay, László Perja, Dănuţ-Georgel Kamal, Kamal Constantin Trăistaru, Magdalena Rodica Kamal, Diana Ciortea, Viorela Mihaela Popa, Theodor Borda, Ileana Monica Ungur, Rodica Ana Ciubean, Alina Deniza Rom J Morphol Embryol Case Report Gout is one of the most common types of inflammatory arthritis. Four stages have been described in its evolution: asymptomatic hyperuricemia, acute gouty arthritis, intercritical gout and chronic tophaceous gout. Monosodium urate crystals deposits are more frequently encountered in hyaline cartilage, tendon sheaths, articular bursae, bone epiphysis, synovium, and skin. Pathological fractures that occur at the formation sites of gout tophi have been rarely described in gout. Bimalleolar fractures often occur following a trauma. We present the case of a 56-year-old patient, diagnosed with chronic gout for over 12 years, with tophi in the upper and lower limbs, who presented accusing mechanical pain in the left tibio-tarsal joint and impaired function of the hands. The clinical examination showed bilateral multiple destructive gout tophi in the hands, forearms, elbows, feet, ankles, and lower legs, while the left ankle exhibited an important varus deformity. Computed tomography examination of the left ankle showed multiple gout tophi with bone erosions and a bimalleolar pathological fracture. The patient underwent pharmacological treatment, physical therapy and the ankle was immobilized in a knee-ankle-foot orthosis, with subsequent orthopedic surgical treatment for fracture fixation, to improve functional status. We have chosen to present this case given the multiple disabilities of the patient, which have improved following the rehabilitation treatment. Academy of Medical Sciences, Romanian Academy Publishing House, Bucharest 2021 2021-11-22 /pmc/articles/PMC8848262/ /pubmed/35024751 http://dx.doi.org/10.47162/RJME.62.2.29 Text en Copyright © 2020, Academy of Medical Sciences, Romanian Academy Publishing House, Bucharest https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open-access article distributed under the terms of a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International Public License, which permits unrestricted use, adaptation, distribution and reproduction in any medium, non-commercially, provided the new creations are licensed under identical terms as the original work and the original work is properly cited.
spellingShingle Case Report
Irsay, László
Perja, Dănuţ-Georgel
Kamal, Kamal Constantin
Trăistaru, Magdalena Rodica
Kamal, Diana
Ciortea, Viorela Mihaela
Popa, Theodor
Borda, Ileana Monica
Ungur, Rodica Ana
Ciubean, Alina Deniza
Bimalleolar pathological fracture in a patient with chronic tophaceous gout
title Bimalleolar pathological fracture in a patient with chronic tophaceous gout
title_full Bimalleolar pathological fracture in a patient with chronic tophaceous gout
title_fullStr Bimalleolar pathological fracture in a patient with chronic tophaceous gout
title_full_unstemmed Bimalleolar pathological fracture in a patient with chronic tophaceous gout
title_short Bimalleolar pathological fracture in a patient with chronic tophaceous gout
title_sort bimalleolar pathological fracture in a patient with chronic tophaceous gout
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8848262/
https://www.ncbi.nlm.nih.gov/pubmed/35024751
http://dx.doi.org/10.47162/RJME.62.2.29
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