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Characterization of complete Currarino syndrome in pediatrics—a comparison between CT and MRI

BACKGROUND: This study sought to analyze the computed tomography (CT) and magnetic resonance imaging (MRI) characteristics of the classical triad elements and the associated anomalies in pediatric complete Currarino syndrome (CS) to evaluate the advantages and disadvantages of the 2 different imagin...

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Autores principales: Chen, Jing, Zheng, Nannan, Wang, Chunxiang, Shao, Jianbo, Qi, Xin, Xie, Yingjie, Zhang, Quan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8848446/
https://www.ncbi.nlm.nih.gov/pubmed/35282111
http://dx.doi.org/10.21037/atm-21-6572
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author Chen, Jing
Zheng, Nannan
Wang, Chunxiang
Shao, Jianbo
Qi, Xin
Xie, Yingjie
Zhang, Quan
author_facet Chen, Jing
Zheng, Nannan
Wang, Chunxiang
Shao, Jianbo
Qi, Xin
Xie, Yingjie
Zhang, Quan
author_sort Chen, Jing
collection PubMed
description BACKGROUND: This study sought to analyze the computed tomography (CT) and magnetic resonance imaging (MRI) characteristics of the classical triad elements and the associated anomalies in pediatric complete Currarino syndrome (CS) to evaluate the advantages and disadvantages of the 2 different imaging methods in displaying the abnormalities of this disease. METHODS: The clinical and radiological features of 32 pediatric patients with complete CS diagnosed histologically and/or radiologically were retrospectively analyzed. RESULTS: All 32 complete CS patients presented with the classical triad of congenital anorectal malformation (ARM), sacral agenesis, and presacral mass. Anal atresia, which is the most common congenital ARM, was observed in 19 of the 32 patients (59.4%). Sacral agenesis was mainly type IV (75%). Among the presacral masses, true tumors and pseudotumors accounted for about half each. All of the 15 true tumors were presacral teratomas. Twenty-five patients had associated anomalies, including tethered cord, filum lipoma, and hydronephrosis. Twenty-four patients underwent both CT and MRI examinations. While CT was better than MRI in displaying sacral anomaly (P<0.05), MRI was more sensitive than CT at detecting presacral mass, spinal dysraphism, and congenital anal atresia (P<0.05). CONCLUSIONS: CT and MRI have different efficiencies at displaying the abnormalities of the complete CS. As a non-invasive method, MRI has significant advantages in diagnosing complete CS, especially in revealing the details of ARM, presacral mass, and associated spinal dysraphism.
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spelling pubmed-88484462022-03-10 Characterization of complete Currarino syndrome in pediatrics—a comparison between CT and MRI Chen, Jing Zheng, Nannan Wang, Chunxiang Shao, Jianbo Qi, Xin Xie, Yingjie Zhang, Quan Ann Transl Med Original Article BACKGROUND: This study sought to analyze the computed tomography (CT) and magnetic resonance imaging (MRI) characteristics of the classical triad elements and the associated anomalies in pediatric complete Currarino syndrome (CS) to evaluate the advantages and disadvantages of the 2 different imaging methods in displaying the abnormalities of this disease. METHODS: The clinical and radiological features of 32 pediatric patients with complete CS diagnosed histologically and/or radiologically were retrospectively analyzed. RESULTS: All 32 complete CS patients presented with the classical triad of congenital anorectal malformation (ARM), sacral agenesis, and presacral mass. Anal atresia, which is the most common congenital ARM, was observed in 19 of the 32 patients (59.4%). Sacral agenesis was mainly type IV (75%). Among the presacral masses, true tumors and pseudotumors accounted for about half each. All of the 15 true tumors were presacral teratomas. Twenty-five patients had associated anomalies, including tethered cord, filum lipoma, and hydronephrosis. Twenty-four patients underwent both CT and MRI examinations. While CT was better than MRI in displaying sacral anomaly (P<0.05), MRI was more sensitive than CT at detecting presacral mass, spinal dysraphism, and congenital anal atresia (P<0.05). CONCLUSIONS: CT and MRI have different efficiencies at displaying the abnormalities of the complete CS. As a non-invasive method, MRI has significant advantages in diagnosing complete CS, especially in revealing the details of ARM, presacral mass, and associated spinal dysraphism. AME Publishing Company 2022-01 /pmc/articles/PMC8848446/ /pubmed/35282111 http://dx.doi.org/10.21037/atm-21-6572 Text en 2022 Annals of Translational Medicine. All rights reserved. https://creativecommons.org/licenses/by-nc-nd/4.0/Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0 (https://creativecommons.org/licenses/by-nc-nd/4.0/) .
spellingShingle Original Article
Chen, Jing
Zheng, Nannan
Wang, Chunxiang
Shao, Jianbo
Qi, Xin
Xie, Yingjie
Zhang, Quan
Characterization of complete Currarino syndrome in pediatrics—a comparison between CT and MRI
title Characterization of complete Currarino syndrome in pediatrics—a comparison between CT and MRI
title_full Characterization of complete Currarino syndrome in pediatrics—a comparison between CT and MRI
title_fullStr Characterization of complete Currarino syndrome in pediatrics—a comparison between CT and MRI
title_full_unstemmed Characterization of complete Currarino syndrome in pediatrics—a comparison between CT and MRI
title_short Characterization of complete Currarino syndrome in pediatrics—a comparison between CT and MRI
title_sort characterization of complete currarino syndrome in pediatrics—a comparison between ct and mri
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8848446/
https://www.ncbi.nlm.nih.gov/pubmed/35282111
http://dx.doi.org/10.21037/atm-21-6572
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