Cargando…

Epigenetic therapy with chidamide alone or combined with 5-azacitidine exerts antitumour effects on acute myeloid leukaemia cells in vitro

Chidamide, a selective histone deacetylase inhibitor, has antitumour effects. 5-azacitidine (5-AZA), a hypomethylating agent, is effective in treating acute myeloid leukaemia (AML) and myelodysplastic syndrome. However, to the best of our knowledge, the effect of chidamide and 5-AZA on AML cell line...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Zheng, Zhang, Jian, Zhou, Min, Li, Jin-Li, Qiu, Qiao-Cheng, Fu, Jian-Hong, Xue, Sheng-Li, Qiu, Hui-Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8848469/
https://www.ncbi.nlm.nih.gov/pubmed/35103292
http://dx.doi.org/10.3892/or.2022.8277