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Neutrophil to C-reactive protein ratio: An estimating factor for intestinal ischemia before the surgery of incarcerated inguinal hernia

OBJECTIVE: An inguinal hernia may transform to an incarcerated hernia, which would require emergency surgery with increased morbidity and mortality. This study aims to analyze whether it is possible to predict intestinal ischemia in incarcerated hernia using complete blood count parameters and serum...

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Autores principales: Eyvaz, Kemal, Dincer, Onur Ilkay, Kazim Kazan, Murat, Dincer, Aydın, Aslaner, Arif, Acar, Aylin, Cakir, Tugrul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Health Directorate of Istanbul 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8848489/
https://www.ncbi.nlm.nih.gov/pubmed/35284784
http://dx.doi.org/10.14744/nci.2021.26878
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author Eyvaz, Kemal
Dincer, Onur Ilkay
Kazim Kazan, Murat
Dincer, Aydın
Aslaner, Arif
Acar, Aylin
Cakir, Tugrul
author_facet Eyvaz, Kemal
Dincer, Onur Ilkay
Kazim Kazan, Murat
Dincer, Aydın
Aslaner, Arif
Acar, Aylin
Cakir, Tugrul
author_sort Eyvaz, Kemal
collection PubMed
description OBJECTIVE: An inguinal hernia may transform to an incarcerated hernia, which would require emergency surgery with increased morbidity and mortality. This study aims to analyze whether it is possible to predict intestinal ischemia in incarcerated hernia using complete blood count parameters and serum C-reactive protein (CRP). METHODS: Medical records of 129 patients were used to analyze whether there is a correlation between intestinal ischemia and laboratory parameters. Receiver operating characteristics analysis and Youden index were used to determine cutoff values, sensitivity, and specificity. RESULTS: Female patients, those with a femoral type hernia, and patients with additional diseases were found to be more prone to bowel resection. CRP, lymphocyte to CRP ratio (LCR), and neutrophil to CRP ratio (NCR) parameters were significant (AUC=0.914, p<0.001; AUC=0.901, p<0.001; and AUC=0.908, p<0.001, respectively). A value <0.45 for NCR has a sensitivity of 93.3% and specificity of 87.8%; a value >19 in CRP has a 90% sensitivity and 88.9% specificity. CONCLUSION: Decreased pre-operative NCR and LCR, and increased CRP levels can be used as a predictor for estimating intestinal ischemia.
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spelling pubmed-88484892022-03-11 Neutrophil to C-reactive protein ratio: An estimating factor for intestinal ischemia before the surgery of incarcerated inguinal hernia Eyvaz, Kemal Dincer, Onur Ilkay Kazim Kazan, Murat Dincer, Aydın Aslaner, Arif Acar, Aylin Cakir, Tugrul North Clin Istanb Original Article - General Surgery OBJECTIVE: An inguinal hernia may transform to an incarcerated hernia, which would require emergency surgery with increased morbidity and mortality. This study aims to analyze whether it is possible to predict intestinal ischemia in incarcerated hernia using complete blood count parameters and serum C-reactive protein (CRP). METHODS: Medical records of 129 patients were used to analyze whether there is a correlation between intestinal ischemia and laboratory parameters. Receiver operating characteristics analysis and Youden index were used to determine cutoff values, sensitivity, and specificity. RESULTS: Female patients, those with a femoral type hernia, and patients with additional diseases were found to be more prone to bowel resection. CRP, lymphocyte to CRP ratio (LCR), and neutrophil to CRP ratio (NCR) parameters were significant (AUC=0.914, p<0.001; AUC=0.901, p<0.001; and AUC=0.908, p<0.001, respectively). A value <0.45 for NCR has a sensitivity of 93.3% and specificity of 87.8%; a value >19 in CRP has a 90% sensitivity and 88.9% specificity. CONCLUSION: Decreased pre-operative NCR and LCR, and increased CRP levels can be used as a predictor for estimating intestinal ischemia. Health Directorate of Istanbul 2021-12-31 /pmc/articles/PMC8848489/ /pubmed/35284784 http://dx.doi.org/10.14744/nci.2021.26878 Text en Copyright © by by Istanbul Provincial Directorate of Health - Available online at www.northclinist.com https://creativecommons.org/licenses/by/3.0/This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
spellingShingle Original Article - General Surgery
Eyvaz, Kemal
Dincer, Onur Ilkay
Kazim Kazan, Murat
Dincer, Aydın
Aslaner, Arif
Acar, Aylin
Cakir, Tugrul
Neutrophil to C-reactive protein ratio: An estimating factor for intestinal ischemia before the surgery of incarcerated inguinal hernia
title Neutrophil to C-reactive protein ratio: An estimating factor for intestinal ischemia before the surgery of incarcerated inguinal hernia
title_full Neutrophil to C-reactive protein ratio: An estimating factor for intestinal ischemia before the surgery of incarcerated inguinal hernia
title_fullStr Neutrophil to C-reactive protein ratio: An estimating factor for intestinal ischemia before the surgery of incarcerated inguinal hernia
title_full_unstemmed Neutrophil to C-reactive protein ratio: An estimating factor for intestinal ischemia before the surgery of incarcerated inguinal hernia
title_short Neutrophil to C-reactive protein ratio: An estimating factor for intestinal ischemia before the surgery of incarcerated inguinal hernia
title_sort neutrophil to c-reactive protein ratio: an estimating factor for intestinal ischemia before the surgery of incarcerated inguinal hernia
topic Original Article - General Surgery
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8848489/
https://www.ncbi.nlm.nih.gov/pubmed/35284784
http://dx.doi.org/10.14744/nci.2021.26878
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