Cargando…

Aquaporin 4 deficiency eliminates the beneficial effects of voluntary exercise in a mouse model of Alzheimer's disease

Regular exercise has been shown to reduce the risk of Alzheimer's disease (AD). Our previous study showed that the protein aquaporin 4 (AQP4), which is specifically expressed on the paravascular processes of astrocytes, is necessary for glymphatic clearance of extracellular amyloid beta (Aβ) fr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Yun, Hu, Pan-Pan, Zhai, Shuang, Feng, Wei-Xi, Zhang, Rui, Li, Qian, Marshall, Charles, Xiao, Ming, Wu, Ting
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Wolters Kluwer - Medknow 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8848602/ https://www.ncbi.nlm.nih.gov/pubmed/35142700 http://dx.doi.org/10.4103/1673-5374.335169

Ejemplares similares

Astrocyte remodeling in the beneficial effects of long-term voluntary exercise in Alzheimer’s disease
por: Belaya, Irina, et al.
Publicado: (2020)

Beneficial effect of voluntary physical exercise in Plakophilin2 transgenic mice
por: Hammer, Karin P., et al.
Publicado: (2021)

Aquaporin 4 deletion exacerbates brain impairments in a mouse model of chronic sleep disruption
por: Zhang, Rui, et al.
Publicado: (2019)

Effects of Voluntary Physical Exercise on the Neurovascular Unit in a Mouse Model of Alzheimer’s Disease
por: Andrade-Guerrero, Jesús, et al.
Publicado: (2023)

Daily voluntary exercise enhances pilocarpine‐induced saliva secretion and aquaporin 1 expression in rat submandibular glands
por: Matsuzaki, Kentaro, et al.
Publicado: (2017)

Expression of aquaporins in a transgenic mouse model of Alzheimer's disease
por: Chan, Sic L, et al.
Publicado: (2010)

Cellular Localization of Aquaporin-1 in the Human and Mouse Trigeminal Systems
por: Gao, Junying, et al.
Publicado: (2012)

Beneficial effects of tri-lithium pyrroloquinoline quinonein on behaviors and pathology in a mouse model of Alzheimer’s disease
por: Zhao, Lei, et al.
Publicado: (2012)

TREM2 deficiency eliminates TREM2(+) inflammatory macrophages and ameliorates pathology in Alzheimer’s disease mouse models
por: Jay, Taylor R., et al.
Publicado: (2015)

Multifaceted Roles of Aquaporins in the Pathogenesis of Alzheimer’s Disease
por: Yamada, Kaoru
Publicado: (2023)

The Effects of Glucocorticoid and Voluntary Exercise Treatment on the Development of Thoracolumbar Kyphosis in Dystrophin-Deficient Mice
por: Brereton, Daniel, et al.
Publicado: (2012)

Beneficial effects of resveratrol and exercise training on cardiac and aortic function and structure in the 3xTg mouse model of Alzheimer’s disease
por: Esfandiarei, Mitra, et al.
Publicado: (2019)

Is vitiligo associated with systemic aquaporin-3 deficiency?
por: Chandrashekar, Laxmisha, et al.
Publicado: (2021)

Voluntary Imitation in Alzheimer’s Disease Patients
por: Bisio, Ambra, et al.
Publicado: (2016)

The Neuroprotective Effect of the Association of Aquaporin-4/Glutamate Transporter-1 against Alzheimer's Disease
por: Lan, Yu-Long, et al.
Publicado: (2016)

Beneficial Effect of Voluntary Exercise on Experimental Colitis in Mice Fed a High-Fat Diet: The Role of Irisin, Adiponectin and Proinflammatory Biomarkers
por: Mazur-Bialy, Agnieszka Irena, et al.
Publicado: (2017)

Voluntary Patients in Mental Deficiency Hospitals
Publicado: (1958)

Sequence of Age-Associated Changes to the Mouse Neuromuscular Junction and the Protective Effects of Voluntary Exercise
por: Cheng, Anson, et al.
Publicado: (2013)

The Impact of Voluntary Exercise on Stroke Recovery
por: Lohkamp, Klara J., et al.
Publicado: (2021)

Mechanisms of the Beneficial Effects of Exercise on Brain-Derived Neurotrophic Factor Expression in Alzheimer’s Disease
por: Jaberi, Sama, et al.
Publicado: (2023)

A pilot study investigating the effects of voluntary exercise on capillary stalling and cerebral blood flow in the APP/PS1 mouse model of Alzheimer’s disease
por: Falkenhain, Kaja, et al.
Publicado: (2020)

Aquaporin 4 Expression in the mdx Mouse Diaphragm
por: Hara, Hajime, et al.
Publicado: (2011)

Beneficial effects of a pyrroloquinolinequinone-containing dietary formulation on motor deficiency, cognitive decline and mitochondrial dysfunction in a mouse model of Alzheimer’s disease
por: Sawmiller, Darrell, et al.
Publicado: (2017)

Aquaporin-4 reduces neuropathology in a mouse model of Alzheimer’s disease by remodeling peri-plaque astrocyte structure
por: Smith, Alex J., et al.
Publicado: (2019)

Aquaporin‐4 deficiency reduces TGF‐β1 in mouse midbrains and exacerbates pathology in experimental Parkinson's disease
por: Xue, Xue, et al.
Publicado: (2019)

Tracking of voluntary exercise behaviour over the lifespan
por: van der Zee, Matthijs D., et al.
Publicado: (2019)

Voluntary Exercise Suppresses Choroidal Neovascularization in Mice
por: Makin, Ryan D., et al.
Publicado: (2020)

Voluntary Exercise to Reduce Anxiety Behaviour in Traumatic Brain Injury Shown to Alleviate Inflammatory Brain Response in Mice
por: Hu, Xiaoxuan, et al.
Publicado: (2023)

Metabolic remodeling agents show beneficial effects in the dystrophin-deficient mdx mouse model
por: Jahnke, Vanessa E, et al.
Publicado: (2012)

Occurrence of multi-oocyte follicles in aquaporin 8-deficient mice
por: Su, Weiheng, et al.
Publicado: (2013)

The Role of Aquaporins in Plant Growth under Conditions of Oxygen Deficiency
por: Kudoyarova, Guzel, et al.
Publicado: (2022)

Exercise is not beneficial and may accelerate symptom onset in a mouse model of Huntington’s disease
por: Potter, Michelle C, et al.
Publicado: (2010)

Voluntary Running Improves Behavioral and Structural Abnormalities in a Mouse Model of CDKL5 Deficiency Disorder
por: Mottolese, Nicola, et al.
Publicado: (2023)

Aquaporin-11 (AQP11) Expression in the Mouse Brain
por: Koike, Shin, et al.
Publicado: (2016)

Differential Expressions of Aquaporin Subtypes in the Adult Mouse Testis
por: Mohamed, Elsayed A., et al.
Publicado: (2022)

Voluntary wheel running in dystrophin-deficient (mdx) mice: Relationships between exercise parameters and exacerbation of the dystrophic phenotype
por: Smythe, Gayle M, et al.
Publicado: (2012)

Dramatic impacts on brain pathology, anxiety, and cognitive function in the knock-in APP(NL-G-F) mouse model of Alzheimer disease following long-term voluntary exercise
por: Mehla, Jogender, et al.
Publicado: (2022)

Voluntary Exercise Improves Cardiac Function and Prevents Cardiac Remodeling in a Mouse Model of Dilated Cardiomyopathy
por: Deloux, Robin, et al.
Publicado: (2017)

Intraocular pressure and glaucoma: Is physical exercise beneficial or a risk?
por: McMonnies, Charles William
Publicado: (2016)

Exploring cell membrane water exchange in aquaporin-4-deficient ischemic mouse brain using diffusion-weighted MRI
por: Urushihata, Takuya, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_7bmmd0u2r6ndopdjmv6qlkkt9n