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Placental methylome reveals a 22q13.33 brain regulatory gene locus associated with autism

BACKGROUND: Autism spectrum disorder (ASD) involves complex genetics interacting with the perinatal environment, complicating the discovery of common genetic risk. The epigenetic layer of DNA methylation shows dynamic developmental changes and molecular memory of in utero experiences, particularly i...

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Detalles Bibliográficos
Autores principales:	Zhu, Yihui, Gomez, J. Antonio, Laufer, Benjamin I., Mordaunt, Charles E., Mouat, Julia S., Soto, Daniela C., Dennis, Megan Y., Benke, Kelly S., Bakulski, Kelly M., Dou, John, Marathe, Ria, Jianu, Julia M., Williams, Logan A., Gutierrez Fugón, Orangel J., Walker, Cheryl K., Ozonoff, Sally, Daniels, Jason, Grosvenor, Luke P., Volk, Heather E., Feinberg, Jason I., Fallin, M. Daniele, Hertz-Picciotto, Irva, Schmidt, Rebecca J., Yasui, Dag H., LaSalle, Janine M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8848662/ https://www.ncbi.nlm.nih.gov/pubmed/35168652 http://dx.doi.org/10.1186/s13059-022-02613-1

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