Cargando…

Overexpression of CBS/H(2)S inhibits proliferation and metastasis of colon cancer cells through downregulation of CD44

BACKGROUND: The role of hydrogen sulfide (H(2)S) in cancer biology is controversial, including colorectal cancer. The bell-shaped effect of H(2)S refers to pro-cancer action at lower doses and anti-cancer effect at higher concentrations. We hypothesized that overexpression of cystathionine-beta-synt...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Yuyang, Chen, Shanwen, Zhu, Jing, Guo, Shihao, Yue, Taohua, Xu, Hao, Hu, Jianwen, Huang, Zhihao, Chen, Zeyang, Wang, Pengyuan, Liu, Yucun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Primary Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8848668/ https://www.ncbi.nlm.nih.gov/pubmed/35172821 http://dx.doi.org/10.1186/s12935-022-02512-2

Ejemplares similares

CBS-H(2)S axis preserves the intestinal barrier function by inhibiting COX-2 through sulfhydrating human antigen R in colitis
por: Guo, Shihao, et al.
Publicado: (2022)

Activated gastric cancer-associated fibroblasts contribute to the malignant phenotype and 5-FU resistance via paracrine action in gastric cancer
por: Ma, Yongchen, et al.
Publicado: (2018)

Identification of 6 Hub Proteins and Protein Risk Signature of Colorectal Cancer
por: Yue, Taohua, et al.
Publicado: (2020)

Low expression of SPARC in gastric cancer-associated fibroblasts leads to stemness transformation and 5-fluorouracil resistance in gastric cancer
por: Ma, Yongchen, et al.
Publicado: (2019)

The aging-related risk signature in colorectal cancer
por: Yue, Taohua, et al.
Publicado: (2021)

Endogenous hydrogen sulfide regulates xCT stability through persulfidation of OTUB1 at cysteine 91 in colon cancer cells
por: Chen, Shanwen, et al.
Publicado: (2021)

Two Similar Signatures for Predicting the Prognosis and Immunotherapy Efficacy of Stomach Adenocarcinoma Patients
por: Yue, Taohua, et al.
Publicado: (2021)

BCL2A1 and CCL18 Are Predictive Biomarkers of Cisplatin Chemotherapy and Immunotherapy in Colon Cancer Patients
por: Yue, Taohua, et al.
Publicado: (2022)

Macrophage-derived SPARC Attenuates M2-mediated Pro-tumour Phenotypes
por: Hu, Jianwen, et al.
Publicado: (2020)

Aminooxyacetic acid (AOAA) sensitizes colon cancer cells to oxaliplatin via exaggerating apoptosis induced by ROS
por: Yue, Taohua, et al.
Publicado: (2020)

Autophagy-related IFNG is a prognostic and immunochemotherapeutic biomarker of COAD patients
por: Yue, Taohua, et al.
Publicado: (2023)

The novel long noncoding RNA CRART16 confers cetuximab resistance in colorectal cancer cells by enhancing ERBB3 expression via miR-371a-5p
por: Zhang, Xiaoqian, et al.
Publicado: (2020)

H19 Overexpression Induces Resistance to 1,25(OH)2D3 by Targeting VDR Through miR-675-5p in Colon Cancer Cells
por: Chen, Shanwen, et al.
Publicado: (2017)

Long non-coding RNA lncTCF7 activates the Wnt/β-catenin pathway to promote metastasis and invasion in colorectal cancer
por: Li, Tengyu, et al.
Publicado: (2017)

Escherichia coli Nissle 1917 Protects Intestinal Barrier Function by Inhibiting NF-κB-Mediated Activation of the MLCK-P-MLC Signaling Pathway
por: Guo, Shihao, et al.
Publicado: (2019)

1,25(OH)2D3 Attenuates IL-1β-Induced Epithelial-to-Mesenchymal Transition Through Inhibiting the Expression of lncTCF7
por: Li, Tengyu, et al.
Publicado: (2019)

Overexpression of microRNA-367 inhibits angiogenesis in ovarian cancer by downregulating the expression of LPA1
por: Zheng, Qingling, et al.
Publicado: (2020)

CD44 targets Wnt/β-catenin pathway to mediate the proliferation of K562 cells
por: Chang, Guoqiang, et al.
Publicado: (2013)

GYY4137 Attenuates Sodium Deoxycholate-Induced Intestinal Barrier Injury Both In Vitro and In Vivo
por: Chen, Zeyang, et al.
Publicado: (2019)

miR-429 suppresses cell proliferation, migration and invasion in nasopharyngeal carcinoma by downregulation of TLN1
por: Wang, Zhihui, et al.
Publicado: (2019)

Overexpression of SAPCD2 correlates with proliferation and invasion of colorectal carcinoma cells
por: Luo, Yage, et al.
Publicado: (2020)

Suramin inhibits cell proliferation in ovarian and cervical cancer by downregulating heparanase expression
por: Li, HuaPing, et al.
Publicado: (2015)

CAF promotes chemoresistance through NRP2 in gastric cancer
por: Yang, Yanpeng, et al.
Publicado: (2021)

Overexpression of CENPF correlates with poor prognosis and tumor bone metastasis in breast cancer
por: Sun, Jingbo, et al.
Publicado: (2019)

Rosiglitazone metformin adduct inhibits hepatocellular carcinoma proliferation via activation of AMPK/p21 pathway
por: Liu, Yuyang, et al.
Publicado: (2019)

Overexpression of FES might inhibit cell proliferation, migration, and invasion of osteosarcoma cells
por: Zhao, Yang, et al.
Publicado: (2020)

Downregulated lincRNA HOTAIR expression in ovarian cancer stem cells decreases its tumorgeniesis and metastasis by inhibiting epithelial-mesenchymal transition
por: Wang, Jing, et al.
Publicado: (2015)

Long non-coding RNA LBX2-AS1 enhances glioma proliferation through downregulating microRNA-491-5p
por: Chen, Qunbang, et al.
Publicado: (2020)

Downregulation of Siah1 promotes colorectal cancer cell proliferation and migration by regulating AKT and YAP ubiquitylation and proteasome degradation
por: Xiao, Zhiyuan, et al.
Publicado: (2020)

Alkaline phosphatase downregulation promotes lung adenocarcinoma metastasis via the c-Myc/RhoA axis
por: Lou, Zhefeng, et al.
Publicado: (2021)

Overexpression of cytoplasmic β-catenin inhibits the metastasis of the murine osteosarcoma cell line LM8
por: Kidani, Teruki, et al.
Publicado: (2014)

miR-363 suppresses the proliferation, migration and invasion of clear cell renal cell carcinoma by downregulating S1PR1
por: Xie, Yongpeng, et al.
Publicado: (2020)

Do physical activity levels differ by number of children at home in women aged 25–44 in the general population?
por: Abell, Laura P, et al.
Publicado: (2019)

IRF4 overexpression promotes the transdifferentiation of tregs into macrophage‐like cells to inhibit the development of colon cancer
por: Wang, Jiwei, et al.
Publicado: (2021)

Silencing of PSMC2 inhibits development and metastasis of prostate cancer through regulating proliferation, apoptosis and migration
por: Chen, Qingke, et al.
Publicado: (2021)

Identification of the miRNA signature and key genes in colorectal cancer lymph node metastasis
por: Wang, Xi, et al.
Publicado: (2021)

Overexpression of protein regulator of cytokinesis 1 facilitates tumor growth and indicates unfavorable prognosis of patients with colon cancer
por: Xu, Tianxiang, et al.
Publicado: (2020)

Anatomic variations of the anterosuperior pancreaticoduodenal veins encountered during laparoscopic right hemicolectomy: a retrospective single-center analysis
por: Chen, Shanwen, et al.
Publicado: (2022)

Overexpression of suppressor of zest 12 is associated with cervical node metastasis and unfavorable prognosis in tongue squamous cell carcinoma
por: Hu, Huijun, et al.
Publicado: (2017)

Loss of PR55α promotes proliferation and metastasis by activating MAPK/AKT signaling in hepatocellular carcinoma
por: Zhao, JiangSheng, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_92i925lnh7j8emabtvopui52p1