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Head and Neck Sarcomas-clinicopathological Findings, Treatment Modalities and Its Outcome - A Retrospective Study

INTRODUCTION: Sarcomas are malignant neoplasms constituting an important group of tumours due to their high morbidity and mortality. They can arise either from soft tissue or bone. Soft tissue sarcomas are common, but bone sarcomas are rare. The aims and objective of this study are to carry out the...

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Autores principales: Ram, Hari, Kumar, Satish, Singh, S. N., Kumar, Pramod, Singh, Geeta, Ganguly, Roop, Sagar, Mala, Howlader, Debraj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8848714/
https://www.ncbi.nlm.nih.gov/pubmed/35265499
http://dx.doi.org/10.4103/ams.ams_366_20
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author Ram, Hari
Kumar, Satish
Singh, S. N.
Kumar, Pramod
Singh, Geeta
Ganguly, Roop
Sagar, Mala
Howlader, Debraj
author_facet Ram, Hari
Kumar, Satish
Singh, S. N.
Kumar, Pramod
Singh, Geeta
Ganguly, Roop
Sagar, Mala
Howlader, Debraj
author_sort Ram, Hari
collection PubMed
description INTRODUCTION: Sarcomas are malignant neoplasms constituting an important group of tumours due to their high morbidity and mortality. They can arise either from soft tissue or bone. Soft tissue sarcomas are common, but bone sarcomas are rare. The aims and objective of this study are to carry out the study of head-and-neck sarcomas between January 2006 and May 2020. MATERIALS AND METHODS: Eighty-two patients of head-and-neck sarcoma were included. Study of demographic and clinicopathological characteristics including age, sex, gender, presenting symptoms, origin, primary anatomical location, size, tumour grade, staging, treatment modality, recurrence, metastasis, and patient status during the recent visit. RESULTS: Fifty-six (68.3%) were males and 26 (31.7%) were females. The male/female ratio was 2.28:1. The most affected age group was 0–19 years. Tumour size of >5 cm in greatest dimension was seen in 67.1% cases and tumour size of <5 cm in 32.9%. Chemotherapy + radiotherapy (CT + RT) was given in 23.8% followed by surgery in 13.9%. Recurrence was seen in 19.5% and metastasis in 18.3%. DISCUSSION: Rhabdomyosarcoma was the most predominant histological type. Maximum patients reported in late stage. The most commonly used treatment was the combination of CT and RT. Recurrence was seen in 19.5% and distant metastasis in 18.3% patients. Head-and-neck sarcomas are rare so epidemiological studies involving more cases must be carried out for better understanding and better outcome.
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spelling pubmed-88487142022-03-08 Head and Neck Sarcomas-clinicopathological Findings, Treatment Modalities and Its Outcome - A Retrospective Study Ram, Hari Kumar, Satish Singh, S. N. Kumar, Pramod Singh, Geeta Ganguly, Roop Sagar, Mala Howlader, Debraj Ann Maxillofac Surg Original Article - Retrospective Study INTRODUCTION: Sarcomas are malignant neoplasms constituting an important group of tumours due to their high morbidity and mortality. They can arise either from soft tissue or bone. Soft tissue sarcomas are common, but bone sarcomas are rare. The aims and objective of this study are to carry out the study of head-and-neck sarcomas between January 2006 and May 2020. MATERIALS AND METHODS: Eighty-two patients of head-and-neck sarcoma were included. Study of demographic and clinicopathological characteristics including age, sex, gender, presenting symptoms, origin, primary anatomical location, size, tumour grade, staging, treatment modality, recurrence, metastasis, and patient status during the recent visit. RESULTS: Fifty-six (68.3%) were males and 26 (31.7%) were females. The male/female ratio was 2.28:1. The most affected age group was 0–19 years. Tumour size of >5 cm in greatest dimension was seen in 67.1% cases and tumour size of <5 cm in 32.9%. Chemotherapy + radiotherapy (CT + RT) was given in 23.8% followed by surgery in 13.9%. Recurrence was seen in 19.5% and metastasis in 18.3%. DISCUSSION: Rhabdomyosarcoma was the most predominant histological type. Maximum patients reported in late stage. The most commonly used treatment was the combination of CT and RT. Recurrence was seen in 19.5% and distant metastasis in 18.3% patients. Head-and-neck sarcomas are rare so epidemiological studies involving more cases must be carried out for better understanding and better outcome. Wolters Kluwer - Medknow 2021 2022-02-01 /pmc/articles/PMC8848714/ /pubmed/35265499 http://dx.doi.org/10.4103/ams.ams_366_20 Text en Copyright: © 2022 Annals of Maxillofacial Surgery https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article - Retrospective Study
Ram, Hari
Kumar, Satish
Singh, S. N.
Kumar, Pramod
Singh, Geeta
Ganguly, Roop
Sagar, Mala
Howlader, Debraj
Head and Neck Sarcomas-clinicopathological Findings, Treatment Modalities and Its Outcome - A Retrospective Study
title Head and Neck Sarcomas-clinicopathological Findings, Treatment Modalities and Its Outcome - A Retrospective Study
title_full Head and Neck Sarcomas-clinicopathological Findings, Treatment Modalities and Its Outcome - A Retrospective Study
title_fullStr Head and Neck Sarcomas-clinicopathological Findings, Treatment Modalities and Its Outcome - A Retrospective Study
title_full_unstemmed Head and Neck Sarcomas-clinicopathological Findings, Treatment Modalities and Its Outcome - A Retrospective Study
title_short Head and Neck Sarcomas-clinicopathological Findings, Treatment Modalities and Its Outcome - A Retrospective Study
title_sort head and neck sarcomas-clinicopathological findings, treatment modalities and its outcome - a retrospective study
topic Original Article - Retrospective Study
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8848714/
https://www.ncbi.nlm.nih.gov/pubmed/35265499
http://dx.doi.org/10.4103/ams.ams_366_20
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