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How well does molecular simulation reproduce environment-specific conformations of the intrinsically disordered peptides PLP, TP2 and ONEG?
Understanding the conformational ensembles of intrinsically disordered proteins and peptides (IDPs) in their various biological environments is essential for understanding their mechanisms and functional roles in the proteome, leading to a greater knowledge of, and potential treatments for, a broad...
Autores principales: | Reid, Lauren M., Guzzetti, Ileana, Svensson, Tor, Carlsson, Anna-Carin, Su, Wu, Leek, Tomas, von Sydow, Lena, Czechtizky, Werngard, Miljak, Marija, Verma, Chandra, De Maria, Leonardo, Essex, Jonathan W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8848758/ https://www.ncbi.nlm.nih.gov/pubmed/35308859 http://dx.doi.org/10.1039/d1sc03496k |
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