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Equilibria between conformational states of the Ras oncogene protein revealed by high pressure crystallography
In this work, we experimentally investigate the allosteric transitions between conformational states on the Ras oncogene protein using high pressure crystallography. Ras protein is a small GTPase involved in central regulatory processes occurring in multiple conformational states. Ras acts as a mole...
Autores principales: | Girard, Eric, Lopes, Pedro, Spoerner, Michael, Dhaussy, Anne-Claire, Prangé, Thierry, Kalbitzer, Hans Robert, Colloc'h, Nathalie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8848853/ https://www.ncbi.nlm.nih.gov/pubmed/35308861 http://dx.doi.org/10.1039/d1sc05488k |
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