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Equilibria between conformational states of the Ras oncogene protein revealed by high pressure crystallography

In this work, we experimentally investigate the allosteric transitions between conformational states on the Ras oncogene protein using high pressure crystallography. Ras protein is a small GTPase involved in central regulatory processes occurring in multiple conformational states. Ras acts as a mole...

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Detalles Bibliográficos
Autores principales: Girard, Eric, Lopes, Pedro, Spoerner, Michael, Dhaussy, Anne-Claire, Prangé, Thierry, Kalbitzer, Hans Robert, Colloc'h, Nathalie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8848853/
https://www.ncbi.nlm.nih.gov/pubmed/35308861
http://dx.doi.org/10.1039/d1sc05488k

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