What Is the Role of HSCT in Philadelphia-Chromosome–Positive and Philadelphia-Chromosome–Like ALL in the Tyrosine Kinase Inhibitor Era?

Previously, the outcome of paediatric Philadelphia-chromosome–positive (Ph(+)) ALL treated with conventional chemotherapy alone was poor, necessitating the use of haematopoietic stem cell transplantation (HSCT) for the best outcomes. The recent addition of tyrosine kinase inhibitors (TKIs) alongside...

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Detalles Bibliográficos
Autores principales: Vettenranta, Kim, Dobsinska, Veronika, Kertész, Gabriella, Svec, Peter, Buechner, Jochen, Schultz, Kirk R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pediatrics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8848997/
https://www.ncbi.nlm.nih.gov/pubmed/35186828
http://dx.doi.org/10.3389/fped.2021.807002

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