Mapping the biogenesis of forward programmed megakaryocytes from induced pluripotent stem cells

Platelet deficiency, known as thrombocytopenia, can cause hemorrhage and is treated with platelet transfusions. We developed a system for the production of platelet precursor cells, megakaryocytes, from pluripotent stem cells. These cultures can be maintained for >100 days, implying culture renew...

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Detalles Bibliográficos
Autores principales: Lawrence, Moyra, Shahsavari, Arash, Bornelöv, Susanne, Moreau, Thomas, McDonald, Rebecca, Vallance, Thomas M., Kania, Katarzyna, Paramor, Maike, Baye, James, Perrin, Marion, Steindel, Maike, Jimenez-Gomez, Paula, Penfold, Christopher, Mohorianu, Irina, Ghevaert, Cedric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8849335/
https://www.ncbi.nlm.nih.gov/pubmed/35171685
http://dx.doi.org/10.1126/sciadv.abj8618

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