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Treatment Options for Dupuytren’s Disease: Tips and Tricks

Dupuytren's disease (DD) is a common fibroproliferative condition of the hand. METHODS: Management of DD includes observation, non-operative management, and operative management. Operative treatments include percutaneous needle fasciotomy (PNF), open fasciotomy (OF), Clostridium collagenase his...

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Autores principales: Denkler, Keith A., Park, Keon Min, Alser, Osaid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8849405/
https://www.ncbi.nlm.nih.gov/pubmed/35186619
http://dx.doi.org/10.1097/GOX.0000000000004046
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author Denkler, Keith A.
Park, Keon Min
Alser, Osaid
author_facet Denkler, Keith A.
Park, Keon Min
Alser, Osaid
author_sort Denkler, Keith A.
collection PubMed
description Dupuytren's disease (DD) is a common fibroproliferative condition of the hand. METHODS: Management of DD includes observation, non-operative management, and operative management. Operative treatments include percutaneous needle fasciotomy (PNF), open fasciotomy (OF), Clostridium collagenase histolyticum (CCH) injections, limited fasciectomy (LF) and dermofasciectomy (DF). The various methods of DD treatment are reviewed. RESULTS: We summarize the highlights of each treatment option as well as the strengths and weaknesses. PNF has an immediate improvement, but a higher recurrence rate, potential problematic skin tears, and rare tendon or nerve complications. Limited fasciectomy removes the thickened, diseased tissue but has a more prolonged recovery and has a higher rate of significant complications. Dermofasciectomy has the highest complication rate, and the lowest recurrence. Also, secondary fasciectomy after a previous dermofasciectomy has an unexpected amputation rate as high as 8%. Collagenase injections require two visits, have an increased number of minor side effects such as skin tears, and have rare but significant side effects such as tendon rupture. CONCLUSIONS: This article gives an overview of different treatment options for DD and each of their strengths and weaknesses and provides procedural tips.
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spelling pubmed-88494052022-02-18 Treatment Options for Dupuytren’s Disease: Tips and Tricks Denkler, Keith A. Park, Keon Min Alser, Osaid Plast Reconstr Surg Glob Open Hand Dupuytren's disease (DD) is a common fibroproliferative condition of the hand. METHODS: Management of DD includes observation, non-operative management, and operative management. Operative treatments include percutaneous needle fasciotomy (PNF), open fasciotomy (OF), Clostridium collagenase histolyticum (CCH) injections, limited fasciectomy (LF) and dermofasciectomy (DF). The various methods of DD treatment are reviewed. RESULTS: We summarize the highlights of each treatment option as well as the strengths and weaknesses. PNF has an immediate improvement, but a higher recurrence rate, potential problematic skin tears, and rare tendon or nerve complications. Limited fasciectomy removes the thickened, diseased tissue but has a more prolonged recovery and has a higher rate of significant complications. Dermofasciectomy has the highest complication rate, and the lowest recurrence. Also, secondary fasciectomy after a previous dermofasciectomy has an unexpected amputation rate as high as 8%. Collagenase injections require two visits, have an increased number of minor side effects such as skin tears, and have rare but significant side effects such as tendon rupture. CONCLUSIONS: This article gives an overview of different treatment options for DD and each of their strengths and weaknesses and provides procedural tips. Lippincott Williams & Wilkins 2022-01-27 /pmc/articles/PMC8849405/ /pubmed/35186619 http://dx.doi.org/10.1097/GOX.0000000000004046 Text en Copyright © 2022 The Authors. Published by Wolters Kluwer Health, Inc. on behalf of The American Society of Plastic Surgeons. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND) (https://creativecommons.org/licenses/by-nc-nd/4.0/) , where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.
spellingShingle Hand
Denkler, Keith A.
Park, Keon Min
Alser, Osaid
Treatment Options for Dupuytren’s Disease: Tips and Tricks
title Treatment Options for Dupuytren’s Disease: Tips and Tricks
title_full Treatment Options for Dupuytren’s Disease: Tips and Tricks
title_fullStr Treatment Options for Dupuytren’s Disease: Tips and Tricks
title_full_unstemmed Treatment Options for Dupuytren’s Disease: Tips and Tricks
title_short Treatment Options for Dupuytren’s Disease: Tips and Tricks
title_sort treatment options for dupuytren’s disease: tips and tricks
topic Hand
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8849405/
https://www.ncbi.nlm.nih.gov/pubmed/35186619
http://dx.doi.org/10.1097/GOX.0000000000004046
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