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Efficacy of a dietary supplement in dogs with osteoarthritis: A randomized placebo-controlled, double-blind clinical trial

This study is a randomized, placebo-controlled, double-blinded trial performed to investigate the effects of a dietary supplement containing a mixture of Boswellia serrata Roxb., chlorophyll, green tea extract, glucosamine, chondroitin sulfate, hyaluronic acid, and further in the manuscript: non-hyd...

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Autores principales: Martello, Elisa, Bigliati, Mauro, Adami, Raffaella, Biasibetti, Elena, Bisanzio, Donal, Meineri, Giorgia, Bruni, Natascia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8849458/
https://www.ncbi.nlm.nih.gov/pubmed/35171954
http://dx.doi.org/10.1371/journal.pone.0263971
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author Martello, Elisa
Bigliati, Mauro
Adami, Raffaella
Biasibetti, Elena
Bisanzio, Donal
Meineri, Giorgia
Bruni, Natascia
author_facet Martello, Elisa
Bigliati, Mauro
Adami, Raffaella
Biasibetti, Elena
Bisanzio, Donal
Meineri, Giorgia
Bruni, Natascia
author_sort Martello, Elisa
collection PubMed
description This study is a randomized, placebo-controlled, double-blinded trial performed to investigate the effects of a dietary supplement containing a mixture of Boswellia serrata Roxb., chlorophyll, green tea extract, glucosamine, chondroitin sulfate, hyaluronic acid, and further in the manuscript: non-hydrolised type II collagen in dogs with osteoarthritis (OA). A total of 40 dogs were enrolled in the study, they were randomly divided in control (CTR) and treatment (TRT) groups. The TRT group received the dietary supplement for 60 days. The CTR group received a placebo for the same number of days. All the subjects had veterinary evaluations during the trial and owners were requested to fill in questionnaires on chronic pain using the Helsinki Chronic Pain Index. The product was easy to administer and no side effects were reported. Combining results from veterinarian and owner evaluations, the tested product proved to be significantly beneficial in alleviating pain and in reducing the clinical signs in dogs with OA.
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spelling pubmed-88494582022-02-17 Efficacy of a dietary supplement in dogs with osteoarthritis: A randomized placebo-controlled, double-blind clinical trial Martello, Elisa Bigliati, Mauro Adami, Raffaella Biasibetti, Elena Bisanzio, Donal Meineri, Giorgia Bruni, Natascia PLoS One Research Article This study is a randomized, placebo-controlled, double-blinded trial performed to investigate the effects of a dietary supplement containing a mixture of Boswellia serrata Roxb., chlorophyll, green tea extract, glucosamine, chondroitin sulfate, hyaluronic acid, and further in the manuscript: non-hydrolised type II collagen in dogs with osteoarthritis (OA). A total of 40 dogs were enrolled in the study, they were randomly divided in control (CTR) and treatment (TRT) groups. The TRT group received the dietary supplement for 60 days. The CTR group received a placebo for the same number of days. All the subjects had veterinary evaluations during the trial and owners were requested to fill in questionnaires on chronic pain using the Helsinki Chronic Pain Index. The product was easy to administer and no side effects were reported. Combining results from veterinarian and owner evaluations, the tested product proved to be significantly beneficial in alleviating pain and in reducing the clinical signs in dogs with OA. Public Library of Science 2022-02-16 /pmc/articles/PMC8849458/ /pubmed/35171954 http://dx.doi.org/10.1371/journal.pone.0263971 Text en © 2022 Martello et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Martello, Elisa
Bigliati, Mauro
Adami, Raffaella
Biasibetti, Elena
Bisanzio, Donal
Meineri, Giorgia
Bruni, Natascia
Efficacy of a dietary supplement in dogs with osteoarthritis: A randomized placebo-controlled, double-blind clinical trial
title Efficacy of a dietary supplement in dogs with osteoarthritis: A randomized placebo-controlled, double-blind clinical trial
title_full Efficacy of a dietary supplement in dogs with osteoarthritis: A randomized placebo-controlled, double-blind clinical trial
title_fullStr Efficacy of a dietary supplement in dogs with osteoarthritis: A randomized placebo-controlled, double-blind clinical trial
title_full_unstemmed Efficacy of a dietary supplement in dogs with osteoarthritis: A randomized placebo-controlled, double-blind clinical trial
title_short Efficacy of a dietary supplement in dogs with osteoarthritis: A randomized placebo-controlled, double-blind clinical trial
title_sort efficacy of a dietary supplement in dogs with osteoarthritis: a randomized placebo-controlled, double-blind clinical trial
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8849458/
https://www.ncbi.nlm.nih.gov/pubmed/35171954
http://dx.doi.org/10.1371/journal.pone.0263971
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