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MxB inhibits long interspersed element type 1 retrotransposition
Long interspersed element type 1 (LINE-1, also L1 for short) is the only autonomously transposable element in the human genome. Its insertion into a new genomic site may disrupt the function of genes, potentially causing genetic diseases. Cells have thus evolved a battery of mechanisms to tightly co...
Autores principales: | Huang, Yu, Xu, Fengwen, Mei, Shan, Liu, Xiaoman, Zhao, Fei, Wei, Liang, Fan, Zhangling, Hu, Yamei, Wang, Liming, Ai, Bin, Cen, Shan, Liang, Chen, Guo, Fei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8849481/ https://www.ncbi.nlm.nih.gov/pubmed/35171907 http://dx.doi.org/10.1371/journal.pgen.1010034 |
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