A case of encephalitis following COVID-19 vaccine

We describe the first case of encephalitis following coronavirus disease 2019 (COVID-19) vaccination. Our patient was a 46-year-old Japanese woman who presented with acute onset diplopia. Subsequent magnetic resonance imaging revealed brain stem encephalitis that was rapidly responsive to high dosag...

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Detalles Bibliográficos
Autores principales: Kobayashi, Yuya, Karasawa, Seishu, Ohashi, Nobuhiko, Yamamoto, Kanji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Society of Chemotherapy and The Japanese Association for Infectious Diseases. Published by Elsevier Ltd. 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8849833/
https://www.ncbi.nlm.nih.gov/pubmed/35190257
http://dx.doi.org/10.1016/j.jiac.2022.02.009
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author Kobayashi, Yuya
Karasawa, Seishu
Ohashi, Nobuhiko
Yamamoto, Kanji
author_facet Kobayashi, Yuya
Karasawa, Seishu
Ohashi, Nobuhiko
Yamamoto, Kanji
author_sort Kobayashi, Yuya
collection PubMed
description We describe the first case of encephalitis following coronavirus disease 2019 (COVID-19) vaccination. Our patient was a 46-year-old Japanese woman who presented with acute onset diplopia. Subsequent magnetic resonance imaging revealed brain stem encephalitis that was rapidly responsive to high dosage steroid therapy and completely improved. Although the occurrence of encephalitis after vaccination could have just been a casual temporal association, her symptoms were temporally correlated with two vaccinations. Our case suggests caution and indicates treatment and prognosis, despite no evidence of a causal relationship. Nonetheless, this report emphasizes the enormous benefits of vaccination, which should not be undermined.
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spelling pubmed-88498332022-02-18 A case of encephalitis following COVID-19 vaccine Kobayashi, Yuya Karasawa, Seishu Ohashi, Nobuhiko Yamamoto, Kanji J Infect Chemother Case Report We describe the first case of encephalitis following coronavirus disease 2019 (COVID-19) vaccination. Our patient was a 46-year-old Japanese woman who presented with acute onset diplopia. Subsequent magnetic resonance imaging revealed brain stem encephalitis that was rapidly responsive to high dosage steroid therapy and completely improved. Although the occurrence of encephalitis after vaccination could have just been a casual temporal association, her symptoms were temporally correlated with two vaccinations. Our case suggests caution and indicates treatment and prognosis, despite no evidence of a causal relationship. Nonetheless, this report emphasizes the enormous benefits of vaccination, which should not be undermined. Japanese Society of Chemotherapy and The Japanese Association for Infectious Diseases. Published by Elsevier Ltd. 2022-07 2022-02-17 /pmc/articles/PMC8849833/ /pubmed/35190257 http://dx.doi.org/10.1016/j.jiac.2022.02.009 Text en © 2022 Japanese Society of Chemotherapy and The Japanese Association for Infectious Diseases. Published by Elsevier Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Case Report
Kobayashi, Yuya
Karasawa, Seishu
Ohashi, Nobuhiko
Yamamoto, Kanji
A case of encephalitis following COVID-19 vaccine
title A case of encephalitis following COVID-19 vaccine
title_full A case of encephalitis following COVID-19 vaccine
title_fullStr A case of encephalitis following COVID-19 vaccine
title_full_unstemmed A case of encephalitis following COVID-19 vaccine
title_short A case of encephalitis following COVID-19 vaccine
title_sort case of encephalitis following covid-19 vaccine
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8849833/
https://www.ncbi.nlm.nih.gov/pubmed/35190257
http://dx.doi.org/10.1016/j.jiac.2022.02.009
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