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Evaluation of myocardial performance index in patients with COVID-19: An echocardiographic follow-up study
INTRODUCTION AND OBJECTIVES: Myocardial performance may be impaired in cytokine-mediated immune reactions. The myocardial performance index (MPI) is a practical parameter that reflects systolic and diastolic cardiac function. We aimed to assess the MPI in patients with COVID-19. METHODS: The study p...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Sociedade Portuguesa de Cardiologia. Published by Elsevier España, S.L.U.
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8849847/ https://www.ncbi.nlm.nih.gov/pubmed/35194312 http://dx.doi.org/10.1016/j.repc.2021.03.014 |
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author | Kaya, Hakan Asoglu, Ramazan Afsin, Abdulmecit Tibilli, Hakan Kurt, Ercan Kafadar, Safiye Gulacti, Umut Kafadar, Huseyin |
author_facet | Kaya, Hakan Asoglu, Ramazan Afsin, Abdulmecit Tibilli, Hakan Kurt, Ercan Kafadar, Safiye Gulacti, Umut Kafadar, Huseyin |
author_sort | Kaya, Hakan |
collection | PubMed |
description | INTRODUCTION AND OBJECTIVES: Myocardial performance may be impaired in cytokine-mediated immune reactions. The myocardial performance index (MPI) is a practical parameter that reflects systolic and diastolic cardiac function. We aimed to assess the MPI in patients with COVID-19. METHODS: The study population consisted of 40 healthy controls and 40 patients diagnosed with COVID-19 who had mild pneumonia and did not need intensive care treatment. All participants underwent echocardiographic examination. First, the MPI and laboratory parameters were compared between healthy controls and patients in the acute period of infection. Second, the MPI and laboratory parameters were compared between the acute infection period and after clinical recovery. RESULTS: Compared with healthy controls, patients with COVID-19 had a significantly higher MPI (0.56±0.09 vs. 0.41±0.06, p<0.001), longer isovolumic relaxation time (IRT) (112.3±13.4 vs. 90.6±11.2 ms, p<0.001), longer deceleration time (DT) (182.1±30.6 vs. 160.8±42.7 ms, p=0.003), shorter ejection time (ET) (279.6±20.3 vs. 299.6±34.7 ms, p<0.001) and higher E/A ratio (1.53±0.7 vs. 1.21±0.3, p<0.001). Statistically significantly higher MPI (0.56±0.09 vs. 0.44±0.07, p<0.001), longer IRT (112.3±13.4 vs. 91.8±12.1 ms, p<0.001), longer DT (182.1±30.6 vs. 161.5±43.5 ms, p=0.003), shorter ET 279.6±20.3 vs. 298.8±36.8 ms, p<0.001) and higher E/A ratio (1.53±0.7 vs. 1.22±0.4, p<0.001) were observed during the acute infection period than after clinical recovery. Left ventricular ejection fraction was similar in the controls, during the acute infection period and after clinical recovery. CONCLUSIONS: Subclinical diastolic impairment without systolic involvement may be observed in patients with COVID-19. This impairment may be reversible on clinical recovery. |
format | Online Article Text |
id | pubmed-8849847 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Sociedade Portuguesa de Cardiologia. Published by Elsevier España, S.L.U. |
record_format | MEDLINE/PubMed |
spelling | pubmed-88498472022-02-18 Evaluation of myocardial performance index in patients with COVID-19: An echocardiographic follow-up study Kaya, Hakan Asoglu, Ramazan Afsin, Abdulmecit Tibilli, Hakan Kurt, Ercan Kafadar, Safiye Gulacti, Umut Kafadar, Huseyin Rev Port Cardiol Original Article INTRODUCTION AND OBJECTIVES: Myocardial performance may be impaired in cytokine-mediated immune reactions. The myocardial performance index (MPI) is a practical parameter that reflects systolic and diastolic cardiac function. We aimed to assess the MPI in patients with COVID-19. METHODS: The study population consisted of 40 healthy controls and 40 patients diagnosed with COVID-19 who had mild pneumonia and did not need intensive care treatment. All participants underwent echocardiographic examination. First, the MPI and laboratory parameters were compared between healthy controls and patients in the acute period of infection. Second, the MPI and laboratory parameters were compared between the acute infection period and after clinical recovery. RESULTS: Compared with healthy controls, patients with COVID-19 had a significantly higher MPI (0.56±0.09 vs. 0.41±0.06, p<0.001), longer isovolumic relaxation time (IRT) (112.3±13.4 vs. 90.6±11.2 ms, p<0.001), longer deceleration time (DT) (182.1±30.6 vs. 160.8±42.7 ms, p=0.003), shorter ejection time (ET) (279.6±20.3 vs. 299.6±34.7 ms, p<0.001) and higher E/A ratio (1.53±0.7 vs. 1.21±0.3, p<0.001). Statistically significantly higher MPI (0.56±0.09 vs. 0.44±0.07, p<0.001), longer IRT (112.3±13.4 vs. 91.8±12.1 ms, p<0.001), longer DT (182.1±30.6 vs. 161.5±43.5 ms, p=0.003), shorter ET 279.6±20.3 vs. 298.8±36.8 ms, p<0.001) and higher E/A ratio (1.53±0.7 vs. 1.22±0.4, p<0.001) were observed during the acute infection period than after clinical recovery. Left ventricular ejection fraction was similar in the controls, during the acute infection period and after clinical recovery. CONCLUSIONS: Subclinical diastolic impairment without systolic involvement may be observed in patients with COVID-19. This impairment may be reversible on clinical recovery. Sociedade Portuguesa de Cardiologia. Published by Elsevier España, S.L.U. 2022-06 2022-02-17 /pmc/articles/PMC8849847/ /pubmed/35194312 http://dx.doi.org/10.1016/j.repc.2021.03.014 Text en © 2022 Sociedade Portuguesa de Cardiologia. Published by Elsevier España, S.L.U. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Original Article Kaya, Hakan Asoglu, Ramazan Afsin, Abdulmecit Tibilli, Hakan Kurt, Ercan Kafadar, Safiye Gulacti, Umut Kafadar, Huseyin Evaluation of myocardial performance index in patients with COVID-19: An echocardiographic follow-up study |
title | Evaluation of myocardial performance index in patients with COVID-19: An echocardiographic follow-up study |
title_full | Evaluation of myocardial performance index in patients with COVID-19: An echocardiographic follow-up study |
title_fullStr | Evaluation of myocardial performance index in patients with COVID-19: An echocardiographic follow-up study |
title_full_unstemmed | Evaluation of myocardial performance index in patients with COVID-19: An echocardiographic follow-up study |
title_short | Evaluation of myocardial performance index in patients with COVID-19: An echocardiographic follow-up study |
title_sort | evaluation of myocardial performance index in patients with covid-19: an echocardiographic follow-up study |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8849847/ https://www.ncbi.nlm.nih.gov/pubmed/35194312 http://dx.doi.org/10.1016/j.repc.2021.03.014 |
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