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Cepharanthine Attenuates Early Brain Injury after Subarachnoid Hemorrhage in Mice via Inhibiting 15-Lipoxygenase-1-Mediated Microglia and Endothelial Cell Ferroptosis

BACKGROUND: Ferroptosis is a newly identified form of programmed cell death caused by iron-dependent lipid peroxidation. Our study was designed to determine the expression patterns and role of 15-lipoxygenase-1 (ALOX15) in subarachnoid hemorrhage (SAH) and to investigate whether cepharanthine (CEP)...

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Detalles Bibliográficos
Autores principales:	Gao, Shiqi, Zhou, Liuzhi, Lu, Jianan, Fang, Yuanjian, Wu, Haijian, Xu, Weilin, Pan, Yuanbo, Wang, Junjie, Wang, Xiaoyu, Zhang, Jianmin, Shao, Anwen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8850040/ https://www.ncbi.nlm.nih.gov/pubmed/35186185 http://dx.doi.org/10.1155/2022/4295208

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