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Importance and Relevance of Phytochemicals Present in Galenia africana
Many people in developing countries rely primarily on medicinal plants as their main source of healthcare, particularly for the treatment of skin infections. Despite the widespread use of medicinal plants, there is a lack of literature describing the relevance and risks of exposure of the phytochemi...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8850083/ https://www.ncbi.nlm.nih.gov/pubmed/35186343 http://dx.doi.org/10.1155/2022/5793436 |
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author | Heredia, Dario Green, Ivan Klaasen, Jeremy Rahiman, Farzana |
author_facet | Heredia, Dario Green, Ivan Klaasen, Jeremy Rahiman, Farzana |
author_sort | Heredia, Dario |
collection | PubMed |
description | Many people in developing countries rely primarily on medicinal plants as their main source of healthcare, particularly for the treatment of skin infections. Despite the widespread use of medicinal plants, there is a lack of literature describing the relevance and risks of exposure of the phytochemicals present. Galenia africana has been used traditionally in the form of pastes, decoctions, and lotions to treat wounds and other skin-related ailments. This is a report on the phytochemical composition of G. africana and a review on the pharmacological importance and relevance of these phytochemicals. The major groups of phytochemicals identified in G. africana extracts were aliphatics, aliphatic triterpenoids, fatty acids, flavonoids, and phenolic and tocopherol compounds. These have been found to exhibit medicinal properties, thus highlighting the need to assess the safety of G. africana for topical application. The information related to the safety of the various compounds could indicate the potential risks related to accidental intake of the extract upon topical product applications. This report concludes that the quantities of the phytochemicals present in G. africana should not cause undue risk to human health, which provides comfort to pursue future work on using and developing G. africana as a therapeutic agent. |
format | Online Article Text |
id | pubmed-8850083 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-88500832022-02-17 Importance and Relevance of Phytochemicals Present in Galenia africana Heredia, Dario Green, Ivan Klaasen, Jeremy Rahiman, Farzana Scientifica (Cairo) Review Article Many people in developing countries rely primarily on medicinal plants as their main source of healthcare, particularly for the treatment of skin infections. Despite the widespread use of medicinal plants, there is a lack of literature describing the relevance and risks of exposure of the phytochemicals present. Galenia africana has been used traditionally in the form of pastes, decoctions, and lotions to treat wounds and other skin-related ailments. This is a report on the phytochemical composition of G. africana and a review on the pharmacological importance and relevance of these phytochemicals. The major groups of phytochemicals identified in G. africana extracts were aliphatics, aliphatic triterpenoids, fatty acids, flavonoids, and phenolic and tocopherol compounds. These have been found to exhibit medicinal properties, thus highlighting the need to assess the safety of G. africana for topical application. The information related to the safety of the various compounds could indicate the potential risks related to accidental intake of the extract upon topical product applications. This report concludes that the quantities of the phytochemicals present in G. africana should not cause undue risk to human health, which provides comfort to pursue future work on using and developing G. africana as a therapeutic agent. Hindawi 2022-01-25 /pmc/articles/PMC8850083/ /pubmed/35186343 http://dx.doi.org/10.1155/2022/5793436 Text en Copyright © 2022 Dario Heredia et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Heredia, Dario Green, Ivan Klaasen, Jeremy Rahiman, Farzana Importance and Relevance of Phytochemicals Present in Galenia africana |
title | Importance and Relevance of Phytochemicals Present in Galenia africana |
title_full | Importance and Relevance of Phytochemicals Present in Galenia africana |
title_fullStr | Importance and Relevance of Phytochemicals Present in Galenia africana |
title_full_unstemmed | Importance and Relevance of Phytochemicals Present in Galenia africana |
title_short | Importance and Relevance of Phytochemicals Present in Galenia africana |
title_sort | importance and relevance of phytochemicals present in galenia africana |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8850083/ https://www.ncbi.nlm.nih.gov/pubmed/35186343 http://dx.doi.org/10.1155/2022/5793436 |
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