Cargando…

Importance and Relevance of Phytochemicals Present in Galenia africana

Many people in developing countries rely primarily on medicinal plants as their main source of healthcare, particularly for the treatment of skin infections. Despite the widespread use of medicinal plants, there is a lack of literature describing the relevance and risks of exposure of the phytochemi...

Descripción completa

Detalles Bibliográficos
Autores principales: Heredia, Dario, Green, Ivan, Klaasen, Jeremy, Rahiman, Farzana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8850083/
https://www.ncbi.nlm.nih.gov/pubmed/35186343
http://dx.doi.org/10.1155/2022/5793436
_version_ 1784652529172217856
author Heredia, Dario
Green, Ivan
Klaasen, Jeremy
Rahiman, Farzana
author_facet Heredia, Dario
Green, Ivan
Klaasen, Jeremy
Rahiman, Farzana
author_sort Heredia, Dario
collection PubMed
description Many people in developing countries rely primarily on medicinal plants as their main source of healthcare, particularly for the treatment of skin infections. Despite the widespread use of medicinal plants, there is a lack of literature describing the relevance and risks of exposure of the phytochemicals present. Galenia africana has been used traditionally in the form of pastes, decoctions, and lotions to treat wounds and other skin-related ailments. This is a report on the phytochemical composition of G. africana and a review on the pharmacological importance and relevance of these phytochemicals. The major groups of phytochemicals identified in G. africana extracts were aliphatics, aliphatic triterpenoids, fatty acids, flavonoids, and phenolic and tocopherol compounds. These have been found to exhibit medicinal properties, thus highlighting the need to assess the safety of G. africana for topical application. The information related to the safety of the various compounds could indicate the potential risks related to accidental intake of the extract upon topical product applications. This report concludes that the quantities of the phytochemicals present in G. africana should not cause undue risk to human health, which provides comfort to pursue future work on using and developing G. africana as a therapeutic agent.
format Online
Article
Text
id pubmed-8850083
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Hindawi
record_format MEDLINE/PubMed
spelling pubmed-88500832022-02-17 Importance and Relevance of Phytochemicals Present in Galenia africana Heredia, Dario Green, Ivan Klaasen, Jeremy Rahiman, Farzana Scientifica (Cairo) Review Article Many people in developing countries rely primarily on medicinal plants as their main source of healthcare, particularly for the treatment of skin infections. Despite the widespread use of medicinal plants, there is a lack of literature describing the relevance and risks of exposure of the phytochemicals present. Galenia africana has been used traditionally in the form of pastes, decoctions, and lotions to treat wounds and other skin-related ailments. This is a report on the phytochemical composition of G. africana and a review on the pharmacological importance and relevance of these phytochemicals. The major groups of phytochemicals identified in G. africana extracts were aliphatics, aliphatic triterpenoids, fatty acids, flavonoids, and phenolic and tocopherol compounds. These have been found to exhibit medicinal properties, thus highlighting the need to assess the safety of G. africana for topical application. The information related to the safety of the various compounds could indicate the potential risks related to accidental intake of the extract upon topical product applications. This report concludes that the quantities of the phytochemicals present in G. africana should not cause undue risk to human health, which provides comfort to pursue future work on using and developing G. africana as a therapeutic agent. Hindawi 2022-01-25 /pmc/articles/PMC8850083/ /pubmed/35186343 http://dx.doi.org/10.1155/2022/5793436 Text en Copyright © 2022 Dario Heredia et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Heredia, Dario
Green, Ivan
Klaasen, Jeremy
Rahiman, Farzana
Importance and Relevance of Phytochemicals Present in Galenia africana
title Importance and Relevance of Phytochemicals Present in Galenia africana
title_full Importance and Relevance of Phytochemicals Present in Galenia africana
title_fullStr Importance and Relevance of Phytochemicals Present in Galenia africana
title_full_unstemmed Importance and Relevance of Phytochemicals Present in Galenia africana
title_short Importance and Relevance of Phytochemicals Present in Galenia africana
title_sort importance and relevance of phytochemicals present in galenia africana
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8850083/
https://www.ncbi.nlm.nih.gov/pubmed/35186343
http://dx.doi.org/10.1155/2022/5793436
work_keys_str_mv AT herediadario importanceandrelevanceofphytochemicalspresentingaleniaafricana
AT greenivan importanceandrelevanceofphytochemicalspresentingaleniaafricana
AT klaasenjeremy importanceandrelevanceofphytochemicalspresentingaleniaafricana
AT rahimanfarzana importanceandrelevanceofphytochemicalspresentingaleniaafricana