Mechanisms of inhibition and activation of extrasynaptic αβ GABA(A) receptors

Type A GABA (γ-aminobutyric acid) receptors represent a diverse population in the mammalian brain, forming pentamers from combinations of α-, β-, γ-, δ-, ε-, ρ-, θ- and π-subunits(1). αβ, α4βδ, α6βδ and α5βγ receptors favour extrasynaptic localization, and mediate an essential persistent (tonic) inh...

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Detalles Bibliográficos
Autores principales: Kasaragod, Vikram Babu, Mortensen, Martin, Hardwick, Steven W., Wahid, Ayla A., Dorovykh, Valentina, Chirgadze, Dimitri Y., Smart, Trevor G., Miller, Paul S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8850191/
https://www.ncbi.nlm.nih.gov/pubmed/35140402
http://dx.doi.org/10.1038/s41586-022-04402-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8850191/
https://www.ncbi.nlm.nih.gov/pubmed/35140402
http://dx.doi.org/10.1038/s41586-022-04402-z

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