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Mechanisms of inhibition and activation of extrasynaptic αβ GABA(A) receptors
Type A GABA (γ-aminobutyric acid) receptors represent a diverse population in the mammalian brain, forming pentamers from combinations of α-, β-, γ-, δ-, ε-, ρ-, θ- and π-subunits(1). αβ, α4βδ, α6βδ and α5βγ receptors favour extrasynaptic localization, and mediate an essential persistent (tonic) inh...
Autores principales: | Kasaragod, Vikram Babu, Mortensen, Martin, Hardwick, Steven W., Wahid, Ayla A., Dorovykh, Valentina, Chirgadze, Dimitri Y., Smart, Trevor G., Miller, Paul S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8850191/ https://www.ncbi.nlm.nih.gov/pubmed/35140402 http://dx.doi.org/10.1038/s41586-022-04402-z |
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