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Knockout of ASPP2 promotes DEN-induced hepatocarcinogenesis via the NF-κB pathway in mice
Apoptosis-stimulating protein p53 2 (ASPP2) is a member of the p53-binding protein family, which is closely related to tumor development. However, the precise mechanism of ASPP2 in liver inflammation and tumorigenesis remains largely unclear. We aimed to characterize the mechanistic significance and...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group US
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8850195/ https://www.ncbi.nlm.nih.gov/pubmed/33558702 http://dx.doi.org/10.1038/s41417-021-00300-0 |