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Knockout of ASPP2 promotes DEN-induced hepatocarcinogenesis via the NF-κB pathway in mice

Apoptosis-stimulating protein p53 2 (ASPP2) is a member of the p53-binding protein family, which is closely related to tumor development. However, the precise mechanism of ASPP2 in liver inflammation and tumorigenesis remains largely unclear. We aimed to characterize the mechanistic significance and...

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Detalles Bibliográficos
Autores principales: Wang, Shanshan, Kou, Buxin, Chai, Mengyin, Gao, Yuxue, Lin, Xuejun, Yin, Ling, Chen, Dexi, Liu, Xiaoni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8850195/
https://www.ncbi.nlm.nih.gov/pubmed/33558702
http://dx.doi.org/10.1038/s41417-021-00300-0

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