Structure, mechanism and lipid-mediated remodeling of the mammalian Na(+)/H(+) exchanger NHA2

The Na(+)/H(+) exchanger SLC9B2, also known as NHA2, correlates with the long-sought-after Na(+)/Li(+) exchanger linked to the pathogenesis of diabetes mellitus and essential hypertension in humans. Despite the functional importance of NHA2, structural information and the molecular basis for its ion...

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Detalles Bibliográficos
Autores principales: Matsuoka, Rei, Fudim, Roman, Jung, Sukkyeong, Zhang, Chenou, Bazzone, Andre, Chatzikyriakidou, Yurie, Robinson, Carol V., Nomura, Norimichi, Iwata, So, Landreh, Michael, Orellana, Laura, Beckstein, Oliver, Drew, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8850199/
https://www.ncbi.nlm.nih.gov/pubmed/35173351
http://dx.doi.org/10.1038/s41594-022-00738-2

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