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A novel approach to calculating the kinetically derived maximum dose

The kinetically derived maximal dose (KMD) provides a toxicologically relevant upper range for the determination of chemical safety. Here, we describe a new way of calculating the KMD that is based on sound Bayesian, theoretical, biochemical, and toxicokinetic principles, that avoids the problems of...

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Detalles Bibliográficos
Autores principales:	Burgoon, Lyle D., Fuentes, Claudio, Borgert, Christopher J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2022
Materias:	Toxicokinetics and Metabolism
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8850229/ https://www.ncbi.nlm.nih.gov/pubmed/35103817 http://dx.doi.org/10.1007/s00204-022-03229-x

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