Cargando…

Pro-inflammatory activation changes intracellular transport of bevacizumab in the retinal pigment epithelium in vitro

PURPOSE: Bevacizumab is taken up and transported through the retinal pigment epithelium. Inflammatory signaling may influence this interaction. In the present study, we have investigated the effect of pro-inflammatory stimuli on the uptake, intracellular localization, and transepithelial transport o...

Descripción completa

Detalles Bibliográficos
Autores principales: Hildebrandt, Julia, Käckenmeister, Tom, Winkelmann, Katrin, Dörschmann, Philipp, Roider, Johann, Klettner, Alexa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8850249/
https://www.ncbi.nlm.nih.gov/pubmed/34643794
http://dx.doi.org/10.1007/s00417-021-05443-2