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Pro-inflammatory activation changes intracellular transport of bevacizumab in the retinal pigment epithelium in vitro
PURPOSE: Bevacizumab is taken up and transported through the retinal pigment epithelium. Inflammatory signaling may influence this interaction. In the present study, we have investigated the effect of pro-inflammatory stimuli on the uptake, intracellular localization, and transepithelial transport o...
Autores principales: | Hildebrandt, Julia, Käckenmeister, Tom, Winkelmann, Katrin, Dörschmann, Philipp, Roider, Johann, Klettner, Alexa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8850249/ https://www.ncbi.nlm.nih.gov/pubmed/34643794 http://dx.doi.org/10.1007/s00417-021-05443-2 |
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