A Spontaneous Model of Experimental Autoimmune Encephalomyelitis Provides Evidence of MOG-Specific B Cell Recruitment and Clonal Expansion

The key role of B cells in the pathophysiology of multiple sclerosis (MS) is supported by the presence of oligoclonal bands in the cerebrospinal fluid, by the association of meningeal ectopic B cell follicles with demyelination, axonal loss and reduction of astrocytes, as well as by the high efficac...

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Detalles Bibliográficos
Autores principales: Salvador, Florent, Deramoudt, Laure, Leprêtre, Frédéric, Figeac, Martin, Guerrier, Thomas, Boucher, Julie, Bas, Mathilde, Journiac, Nathalie, Peters, Anneli, Mars, Lennart T., Zéphir, Hélène
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8850296/
https://www.ncbi.nlm.nih.gov/pubmed/35185870
http://dx.doi.org/10.3389/fimmu.2022.755900

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