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Single-cell multiomics reveals heterogeneous cell states linked to metastatic potential in liver cancer cell lines

Hepatocellular carcinoma (HCC) is the most common liver cancer with a high rate of metastasis. However, the molecular mechanisms that drive metastasis remain unclear. We combined single-cell transcriptomic, proteomic, and chromatin accessibility data to investigate how heterogeneous phenotypes contr...

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Detalles Bibliográficos
Autores principales: Wang, Shanshan, Xie, Jiarui, Zou, Xuanxuan, Pan, Taotao, Yu, Qichao, Zhuang, Zhenkun, Zhong, Yu, Zhao, Xin, Wang, Zifei, Li, Rui, Lei, Ying, Yin, Jianhua, Yuan, Yue, Wei, Xiaoyu, Liu, Longqi, Liu, Shiping, Yang, Huanming, Wu, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8850337/
https://www.ncbi.nlm.nih.gov/pubmed/35198910
http://dx.doi.org/10.1016/j.isci.2022.103857

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