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Segmental Tissue Speckle Tracking Predicts the Stenosis Severity in Patients With Coronary Artery Disease

OBJECTIVE: Two-dimensional speckle tracking echocardiography (2D-STE) has been used as a diagnostic tool for coronary artery disease (CAD). However, whether vessel supplied myocardial strain and strain rate (SR) predict the severity of coronary artery stenosis in patients with CAD is unknown. This s...

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Autores principales: Chaichuum, Srisakul, Chiang, Shuo-Ju, Daimon, Masao, Chang, Su-Chen, Chan, Chih-Lin, Hsu, Chu-Ying, Chen, Hsiang-Ho, Tseng, Ching-Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8850403/
https://www.ncbi.nlm.nih.gov/pubmed/35187117
http://dx.doi.org/10.3389/fcvm.2021.832096
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author Chaichuum, Srisakul
Chiang, Shuo-Ju
Daimon, Masao
Chang, Su-Chen
Chan, Chih-Lin
Hsu, Chu-Ying
Chen, Hsiang-Ho
Tseng, Ching-Li
author_facet Chaichuum, Srisakul
Chiang, Shuo-Ju
Daimon, Masao
Chang, Su-Chen
Chan, Chih-Lin
Hsu, Chu-Ying
Chen, Hsiang-Ho
Tseng, Ching-Li
author_sort Chaichuum, Srisakul
collection PubMed
description OBJECTIVE: Two-dimensional speckle tracking echocardiography (2D-STE) has been used as a diagnostic tool for coronary artery disease (CAD). However, whether vessel supplied myocardial strain and strain rate (SR) predict the severity of coronary artery stenosis in patients with CAD is unknown. This study aimed to investigate correlation of cardiac mechanical parameters in tissue speckle tracking measurements with coronary artery stenosis diagnosed by cardiac catheterization in patients with clinically diagnosed CAD. METHODS AND RESULTS: Among 59 patients analyzed, 170 vessels were evaluated by coronary angiography and the corresponding echocardiography to quantify left ventricular myocardial strain and SR. The average longitudinal strain and SR of the segmental myocardium supplied by each coronary artery were calculated to achieve vessel myocardium strain (VMS) and strain rate (VMSR). The VMS and VMSR at each of four severity levels of stenosis showed significant differences among groups (p = 0.016, and p < 0.001, respectively). The strain and SR in vessels with very severe stenosis (≥75%, group IV; n = 29), 13.9 ± 4.3, and 0.9 ± 0.3, respectively, were significantly smaller than those of vessels with mild stenosis ≤ 25%, group I; n = 88, 16.9 ± 4.9, p = 0.023, and 1.2 ± 0.3, p = 0.001, respectively. The SR in vessels with moderate stenosis (26–49%, group II; n = 37), 1.0 ± 0.2, was significantly smaller than that in vessels with mild stenosis vessels (p = 0.021). The lower VMS and VMSR, the higher possibility of severe coronary stenosis is. The VMS and VMSR lower than 13.9 ± 4.3 and 0.9 ± 0.3, respectively predicted the severe coronary stenosis. The VMS and VMSR higher than 16.9 ± 4.9 and 1.2 ± 0.3, respectively predicted mild or no coronary artery stenosis. CONCLUSIONS: The actual stenosis rate in catheterization demonstrates that this technique was able to assess coronary artery condition. Thus, the application of a non-invasive method of 2D-STE to evaluate and simplify diagnosis of CAD is feasible.
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spelling pubmed-88504032022-02-18 Segmental Tissue Speckle Tracking Predicts the Stenosis Severity in Patients With Coronary Artery Disease Chaichuum, Srisakul Chiang, Shuo-Ju Daimon, Masao Chang, Su-Chen Chan, Chih-Lin Hsu, Chu-Ying Chen, Hsiang-Ho Tseng, Ching-Li Front Cardiovasc Med Cardiovascular Medicine OBJECTIVE: Two-dimensional speckle tracking echocardiography (2D-STE) has been used as a diagnostic tool for coronary artery disease (CAD). However, whether vessel supplied myocardial strain and strain rate (SR) predict the severity of coronary artery stenosis in patients with CAD is unknown. This study aimed to investigate correlation of cardiac mechanical parameters in tissue speckle tracking measurements with coronary artery stenosis diagnosed by cardiac catheterization in patients with clinically diagnosed CAD. METHODS AND RESULTS: Among 59 patients analyzed, 170 vessels were evaluated by coronary angiography and the corresponding echocardiography to quantify left ventricular myocardial strain and SR. The average longitudinal strain and SR of the segmental myocardium supplied by each coronary artery were calculated to achieve vessel myocardium strain (VMS) and strain rate (VMSR). The VMS and VMSR at each of four severity levels of stenosis showed significant differences among groups (p = 0.016, and p < 0.001, respectively). The strain and SR in vessels with very severe stenosis (≥75%, group IV; n = 29), 13.9 ± 4.3, and 0.9 ± 0.3, respectively, were significantly smaller than those of vessels with mild stenosis ≤ 25%, group I; n = 88, 16.9 ± 4.9, p = 0.023, and 1.2 ± 0.3, p = 0.001, respectively. The SR in vessels with moderate stenosis (26–49%, group II; n = 37), 1.0 ± 0.2, was significantly smaller than that in vessels with mild stenosis vessels (p = 0.021). The lower VMS and VMSR, the higher possibility of severe coronary stenosis is. The VMS and VMSR lower than 13.9 ± 4.3 and 0.9 ± 0.3, respectively predicted the severe coronary stenosis. The VMS and VMSR higher than 16.9 ± 4.9 and 1.2 ± 0.3, respectively predicted mild or no coronary artery stenosis. CONCLUSIONS: The actual stenosis rate in catheterization demonstrates that this technique was able to assess coronary artery condition. Thus, the application of a non-invasive method of 2D-STE to evaluate and simplify diagnosis of CAD is feasible. Frontiers Media S.A. 2022-02-03 /pmc/articles/PMC8850403/ /pubmed/35187117 http://dx.doi.org/10.3389/fcvm.2021.832096 Text en Copyright © 2022 Chaichuum, Chiang, Daimon, Chang, Chan, Hsu, Chen and Tseng. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Cardiovascular Medicine
Chaichuum, Srisakul
Chiang, Shuo-Ju
Daimon, Masao
Chang, Su-Chen
Chan, Chih-Lin
Hsu, Chu-Ying
Chen, Hsiang-Ho
Tseng, Ching-Li
Segmental Tissue Speckle Tracking Predicts the Stenosis Severity in Patients With Coronary Artery Disease
title Segmental Tissue Speckle Tracking Predicts the Stenosis Severity in Patients With Coronary Artery Disease
title_full Segmental Tissue Speckle Tracking Predicts the Stenosis Severity in Patients With Coronary Artery Disease
title_fullStr Segmental Tissue Speckle Tracking Predicts the Stenosis Severity in Patients With Coronary Artery Disease
title_full_unstemmed Segmental Tissue Speckle Tracking Predicts the Stenosis Severity in Patients With Coronary Artery Disease
title_short Segmental Tissue Speckle Tracking Predicts the Stenosis Severity in Patients With Coronary Artery Disease
title_sort segmental tissue speckle tracking predicts the stenosis severity in patients with coronary artery disease
topic Cardiovascular Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8850403/
https://www.ncbi.nlm.nih.gov/pubmed/35187117
http://dx.doi.org/10.3389/fcvm.2021.832096
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