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The lipid components of high-density lipoproteins (HDL) are essential for the binding and transportation of antimicrobial peptides in human serum

Antimicrobial peptides (AMPs) have been developed for the treatment of bacterial infections, but their applications are limited to topical infections since they are sequestered and inhibited in serum. Here we have discovered that the inhibition of AMPs by human serum was mediated through high-densit...

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Detalles Bibliográficos
Autores principales: Tang, Wen-Hung, Wang, Shi-Han, Wang, Chiu-Feng, Mou, Yun, Lin, Min-Guan, Hsiao, Chwan-Deng, Liao, You-Di
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8850444/
https://www.ncbi.nlm.nih.gov/pubmed/35173253
http://dx.doi.org/10.1038/s41598-022-06640-7