Conserved topology of virus glycoepitopes presents novel targets for repurposing HIV antibody 2G12

Complex glycans decorate viral surface proteins and play a critical role in virus–host interactions. Viral surface glycans shield vulnerable protein epitopes from host immunity yet can also present distinct “glycoepitopes” that can be targeted by host antibodies such as the potent anti-HIV antibody...

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Bibliografiske detaljer
Autores principales: Miller, Nathaniel L., Subramanian, Vidya, Clark, Thomas, Raman, Rahul, Sasisekharan, Ram
Format: Online Artículo Texto
Sprog:English
Udgivet: Nature Publishing Group UK 2022
Fag:
Article
Online adgang:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8850445/
https://www.ncbi.nlm.nih.gov/pubmed/35173180
http://dx.doi.org/10.1038/s41598-022-06157-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8850445/
https://www.ncbi.nlm.nih.gov/pubmed/35173180
http://dx.doi.org/10.1038/s41598-022-06157-z

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