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Conserved topology of virus glycoepitopes presents novel targets for repurposing HIV antibody 2G12
Complex glycans decorate viral surface proteins and play a critical role in virus–host interactions. Viral surface glycans shield vulnerable protein epitopes from host immunity yet can also present distinct “glycoepitopes” that can be targeted by host antibodies such as the potent anti-HIV antibody...
| Auteurs principaux: | , , , , |
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| Format: | Online Article Texte |
| Langue: | English |
| Publié: |
Nature Publishing Group UK
2022
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| Sujets: | |
| Accès en ligne: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8850445/ https://www.ncbi.nlm.nih.gov/pubmed/35173180 http://dx.doi.org/10.1038/s41598-022-06157-z |