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Conserved topology of virus glycoepitopes presents novel targets for repurposing HIV antibody 2G12

Complex glycans decorate viral surface proteins and play a critical role in virus–host interactions. Viral surface glycans shield vulnerable protein epitopes from host immunity yet can also present distinct “glycoepitopes” that can be targeted by host antibodies such as the potent anti-HIV antibody...

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Dettagli Bibliografici
Autori principali: Miller, Nathaniel L., Subramanian, Vidya, Clark, Thomas, Raman, Rahul, Sasisekharan, Ram
Natura: Online Articolo testo
Lingua:English
Pubblicazione: Nature Publishing Group UK 2022
Soggetti:
Accesso online:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8850445/
https://www.ncbi.nlm.nih.gov/pubmed/35173180
http://dx.doi.org/10.1038/s41598-022-06157-z