Abacavir inhibits but does not cause self-reactivity to HLA-B*57:01-restricted EBV specific T cell receptors

Pre-existing pathogen-specific memory T cell responses can contribute to multiple adverse outcomes including autoimmunity and drug hypersensitivity. How the specificity of the T cell receptor (TCR) is subverted or seconded in many of these diseases remains unclear. Here, we apply abacavir hypersensi...

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Detalles Bibliográficos
Autores principales: Sooda, Anuradha, Rwandamuriye, Francois, Wanjalla, Celestine N., Jing, Lichen, Koelle, David M., Peters, Bjoern, Leary, Shay, Chopra, Abha, Calderwood, Michael A., Mallal, Simon A., Pavlos, Rebecca, Watson, Mark, Phillips, Elizabeth J., Redwood, Alec J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8850454/
https://www.ncbi.nlm.nih.gov/pubmed/35173258
http://dx.doi.org/10.1038/s42003-022-03058-9

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