Nanoscale Drug Delivery Systems in Glioblastoma

Glioblastoma is the most aggressive cerebral tumor in adults. However, the current pharmaceuticals in GBM treatment are mainly restricted to few chemotherapeutic drugs and have limited efficacy. Therefore, various nanoscale biomaterials that possess distinct structure and unique property were constr...

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Autores principales: Liu, Zihao, Ji, Xiaoshuai, He, Dong, Zhang, Rui, Liu, Qian, Xin, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8850533/
https://www.ncbi.nlm.nih.gov/pubmed/35171358
http://dx.doi.org/10.1186/s11671-022-03668-6
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author Liu, Zihao
Ji, Xiaoshuai
He, Dong
Zhang, Rui
Liu, Qian
Xin, Tao
author_facet Liu, Zihao
Ji, Xiaoshuai
He, Dong
Zhang, Rui
Liu, Qian
Xin, Tao
author_sort Liu, Zihao
collection PubMed
description Glioblastoma is the most aggressive cerebral tumor in adults. However, the current pharmaceuticals in GBM treatment are mainly restricted to few chemotherapeutic drugs and have limited efficacy. Therefore, various nanoscale biomaterials that possess distinct structure and unique property were constructed as vehicles to precisely deliver molecules with potential therapeutic effect. In this review, nanoparticle drug delivery systems including CNTs, GBNs, C-dots, MOFs, Liposomes, MSNs, GNPs, PMs, Dendrimers and Nanogel were exemplified. The advantages and disadvantages of these nanoparticles in GBM treatment were illustrated. [Image: see text]
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spelling pubmed-88505332022-02-23 Nanoscale Drug Delivery Systems in Glioblastoma Liu, Zihao Ji, Xiaoshuai He, Dong Zhang, Rui Liu, Qian Xin, Tao Nanoscale Res Lett Review Glioblastoma is the most aggressive cerebral tumor in adults. However, the current pharmaceuticals in GBM treatment are mainly restricted to few chemotherapeutic drugs and have limited efficacy. Therefore, various nanoscale biomaterials that possess distinct structure and unique property were constructed as vehicles to precisely deliver molecules with potential therapeutic effect. In this review, nanoparticle drug delivery systems including CNTs, GBNs, C-dots, MOFs, Liposomes, MSNs, GNPs, PMs, Dendrimers and Nanogel were exemplified. The advantages and disadvantages of these nanoparticles in GBM treatment were illustrated. [Image: see text] Springer US 2022-02-16 /pmc/articles/PMC8850533/ /pubmed/35171358 http://dx.doi.org/10.1186/s11671-022-03668-6 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Review
Liu, Zihao
Ji, Xiaoshuai
He, Dong
Zhang, Rui
Liu, Qian
Xin, Tao
Nanoscale Drug Delivery Systems in Glioblastoma
title Nanoscale Drug Delivery Systems in Glioblastoma
title_full Nanoscale Drug Delivery Systems in Glioblastoma
title_fullStr Nanoscale Drug Delivery Systems in Glioblastoma
title_full_unstemmed Nanoscale Drug Delivery Systems in Glioblastoma
title_short Nanoscale Drug Delivery Systems in Glioblastoma
title_sort nanoscale drug delivery systems in glioblastoma
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8850533/
https://www.ncbi.nlm.nih.gov/pubmed/35171358
http://dx.doi.org/10.1186/s11671-022-03668-6
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AT hedong nanoscaledrugdeliverysystemsinglioblastoma
AT zhangrui nanoscaledrugdeliverysystemsinglioblastoma
AT liuqian nanoscaledrugdeliverysystemsinglioblastoma
AT xintao nanoscaledrugdeliverysystemsinglioblastoma

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