Ailanthone Inhibits Proliferation, Migration and Invasion of Osteosarcoma Cells by Downregulating the Serine Biosynthetic Pathway

Osteosarcoma (OS) is the most common primary bone sarcoma, chemoresistance becomes an obstacle to its treatment. Metabolic reprogramming is a hallmark of malignancy, targeting the metabolic pathways might provide a reasonable therapeutic strategy for OS. Here we demonstrated that Ailanthone (AIL), a...

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Detalles Bibliográficos
Autores principales: Zhang, Yawen, Gong, Runze, Liu, Yong, Sun, Xipeng, Liang, Jinrong, Zhou, Yan, Wang, Yaling, Yu, Wenxi, Wang, Yonggang, Tang, Lina, He, Aina, Shen, Zan, Yao, Yang, Hu, Haiyan, Liu, Xin, Zhang, Jianjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8850634/
https://www.ncbi.nlm.nih.gov/pubmed/35186770
http://dx.doi.org/10.3389/fonc.2022.842406

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