The Role of the EZH2 and H3K27me3 Expression as a Predictor of Clinical Outcomes in Salivary Duct Carcinoma Patients: A Large-Series Study With Emphasis on the Relevance to the Combined Androgen Blockade and HER2-Targeted Therapy

OBJECTIVE: Salivary duct carcinoma (SDC) is a highly aggressive and uncommon tumor arising not only de novo but also in pleomorphic adenoma. Androgen receptor (AR)- and HER2-targeted therapy have recently been introduced for SDC as promising treatment options; however, no predictive biomarkers have...

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Detalles Bibliográficos
Autores principales: Saigusa, Natsuki, Hirai, Hideaki, Tada, Yuichiro, Kawakita, Daisuke, Nakaguro, Masato, Tsukahara, Kiyoaki, Kano, Satoshi, Ozawa, Hiroyuki, Kondo, Takahito, Okami, Kenji, Togashi, Takafumi, Sato, Yukiko, Urano, Makoto, Kajiwara, Manami, Shimura, Tomotaka, Fushimi, Chihiro, Shimizu, Akira, Okamoto, Isaku, Okada, Takuro, Suzuki, Takayoshi, Imanishi, Yorihisa, Watanabe, Yoshihiro, Sakai, Akihiro, Ebisumoto, Koji, Sato, Yuichiro, Honma, Yoshitaka, Yamazaki, Keisuke, Ueki, Yushi, Hanazawa, Toyoyuki, Saito, Yuki, Takahashi, Hideaki, Ando, Mizuo, Kohsaka, Shinji, Matsuki, Takashi, Nagao, Toshitaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8850643/
https://www.ncbi.nlm.nih.gov/pubmed/35186711
http://dx.doi.org/10.3389/fonc.2021.779882

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