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Towards a qAOP framework for predictive toxicology - Linking data to decisions
The adverse outcome pathway (AOP) is a conceptual construct that facilitates organisation and interpretation of mechanistic data representing multiple biological levels and deriving from a range of methodological approaches including in silico, in vitro and in vivo assays. AOPs are playing an increa...
Autores principales: | Paini, Alicia, Campia, Ivana, Cronin, Mark T.D., Asturiol, David, Ceriani, Lidia, Exner, Thomas E., Gao, Wang, Gomes, Caroline, Kruisselbrink, Johannes, Martens, Marvin, Meek, M.E. Bette, Pamies, David, Pletz, Julia, Scholz, Stefan, Schüttler, Andreas, Spînu, Nicoleta, Villeneuve, Daniel L., Wittwehr, Clemens, Worth, Andrew, Luijten, Mirjam |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier B.V
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8850654/ https://www.ncbi.nlm.nih.gov/pubmed/35211660 http://dx.doi.org/10.1016/j.comtox.2021.100195 |
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