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Inhibition of DNA-PK may improve response to neoadjuvant chemoradiotherapy in rectal cancer()()

Treatment of locally advanced rectal cancer includes chemoradiation and surgery, but patient response to treatment is variable. Patients who have a complete response have improved outcomes; therefore, there is a critical need to identify mechanisms of resistance to circumvent them. DNA-PK is involve...

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Detalles Bibliográficos
Autores principales: Smithson, Mary, Irwin, Regina K., Williams, Gregory, McLeod, M. Chandler, Choi, E. Karen, Ganguly, Anutosh, Pepple, Ashley, Cho, Clifford S., Willey, Christopher D., Leopold, Judith, Hardiman, Karin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8850661/
https://www.ncbi.nlm.nih.gov/pubmed/35168148
http://dx.doi.org/10.1016/j.neo.2022.01.004

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