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Inhibition of DNA-PK may improve response to neoadjuvant chemoradiotherapy in rectal cancer()()
Treatment of locally advanced rectal cancer includes chemoradiation and surgery, but patient response to treatment is variable. Patients who have a complete response have improved outcomes; therefore, there is a critical need to identify mechanisms of resistance to circumvent them. DNA-PK is involve...
Autores principales: | Smithson, Mary, Irwin, Regina K., Williams, Gregory, McLeod, M. Chandler, Choi, E. Karen, Ganguly, Anutosh, Pepple, Ashley, Cho, Clifford S., Willey, Christopher D., Leopold, Judith, Hardiman, Karin M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Neoplasia Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8850661/ https://www.ncbi.nlm.nih.gov/pubmed/35168148 http://dx.doi.org/10.1016/j.neo.2022.01.004 |
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