Macrophage-derived IL-6 trans-signalling as a novel target in the pathogenesis of bronchopulmonary dysplasia

RATIONALE: Premature infants exposed to oxygen are at risk for bronchopulmonary dysplasia (BPD), which is characterised by lung growth arrest. Inflammation is important, but the mechanisms remain elusive. Here, we investigated inflammatory pathways and therapeutic targets in severe clinical and expe...

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Detalles Bibliográficos
Autores principales: Hirani, Dharmesh, Alvira, Cristina M., Danopoulos, Soula, Milla, Carlos, Donato, Michele, Tian, Lu, Mohr, Jasmine, Dinger, Katharina, Vohlen, Christina, Selle, Jaco, v. Koningsbruggen-Rietschel, Silke, Barbarino, Verena, Pallasch, Christian, Rose-John, Stefan, Odenthal, Margarete, Pryhuber, Gloria S., Mansouri, Siavash, Savai, Rajkumar, Seeger, Werner, Khatri, Purvesh, Al Alam, Denise, Dötsch, Jörg, Alejandre Alcazar, Miguel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Respiratory Society 2022
Materias:
Original Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8850688/
https://www.ncbi.nlm.nih.gov/pubmed/34446466
http://dx.doi.org/10.1183/13993003.02248-2020

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