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Inflammatory myofibroblastic tumour: case report of a rare form of bladder tumour

INTRODUCTION AND IMPORTANCE: Inflammatory myofibroblastic tumour (IMT) is a rare tumour with malignant potential and has been described in many major organs with the most frequent site being the lungs. However, bladder is an extremely rare location. IMT presents a unique diagnostic challenge because...

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Autores principales: Balagobi, Balasingam, Gobishangar, Sreekanthan, Ginige, Anusha, Gamlaksha, Dayal, Sanjeyan, Jeyarajah, Suvethini, Loganathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8850735/
https://www.ncbi.nlm.nih.gov/pubmed/35158231
http://dx.doi.org/10.1016/j.ijscr.2022.106786
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author Balagobi, Balasingam
Gobishangar, Sreekanthan
Ginige, Anusha
Gamlaksha, Dayal
Sanjeyan, Jeyarajah
Suvethini, Loganathan
author_facet Balagobi, Balasingam
Gobishangar, Sreekanthan
Ginige, Anusha
Gamlaksha, Dayal
Sanjeyan, Jeyarajah
Suvethini, Loganathan
author_sort Balagobi, Balasingam
collection PubMed
description INTRODUCTION AND IMPORTANCE: Inflammatory myofibroblastic tumour (IMT) is a rare tumour with malignant potential and has been described in many major organs with the most frequent site being the lungs. However, bladder is an extremely rare location. IMT presents a unique diagnostic challenge because of the characteristics it shares with malignant neoplasms. CASE PRESENTATION: Here we report the case of a 47-yearold male who presented with storage lower urinary tract symptoms associated with non-specific lower abdominal pain for one month duration. Contrast-enhanced computed tomography of abdomen and pelvis revealed a 6 cm tumour at the dome and left side anterior wall of the bladder. He underwent laparotomy and partial cystectomy. Histopathology results were consistent with an IMT. CLINICAL DISCUSSION: Even though bladder IMT is indolent in course, typical IMTs can be locally aggressive. Due to the lack of specificity in clinical symptoms, it is not easy to arrive at a precise diagnosis before surgery. Hence, the final diagnosis depends on histomorphological features and the immune histochemical profile. CONCLUSION: It can be challenging to distinguish IMT from malignant neoplasms both clinically and histologically. As such, local surgical resection with close follow-up remains the mainstay of treatment for urinary tract IMT.
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spelling pubmed-88507352022-02-22 Inflammatory myofibroblastic tumour: case report of a rare form of bladder tumour Balagobi, Balasingam Gobishangar, Sreekanthan Ginige, Anusha Gamlaksha, Dayal Sanjeyan, Jeyarajah Suvethini, Loganathan Int J Surg Case Rep Case Report INTRODUCTION AND IMPORTANCE: Inflammatory myofibroblastic tumour (IMT) is a rare tumour with malignant potential and has been described in many major organs with the most frequent site being the lungs. However, bladder is an extremely rare location. IMT presents a unique diagnostic challenge because of the characteristics it shares with malignant neoplasms. CASE PRESENTATION: Here we report the case of a 47-yearold male who presented with storage lower urinary tract symptoms associated with non-specific lower abdominal pain for one month duration. Contrast-enhanced computed tomography of abdomen and pelvis revealed a 6 cm tumour at the dome and left side anterior wall of the bladder. He underwent laparotomy and partial cystectomy. Histopathology results were consistent with an IMT. CLINICAL DISCUSSION: Even though bladder IMT is indolent in course, typical IMTs can be locally aggressive. Due to the lack of specificity in clinical symptoms, it is not easy to arrive at a precise diagnosis before surgery. Hence, the final diagnosis depends on histomorphological features and the immune histochemical profile. CONCLUSION: It can be challenging to distinguish IMT from malignant neoplasms both clinically and histologically. As such, local surgical resection with close follow-up remains the mainstay of treatment for urinary tract IMT. Elsevier 2022-01-24 /pmc/articles/PMC8850735/ /pubmed/35158231 http://dx.doi.org/10.1016/j.ijscr.2022.106786 Text en © 2022 Published by Elsevier Ltd on behalf of IJS Publishing Group Ltd. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Balagobi, Balasingam
Gobishangar, Sreekanthan
Ginige, Anusha
Gamlaksha, Dayal
Sanjeyan, Jeyarajah
Suvethini, Loganathan
Inflammatory myofibroblastic tumour: case report of a rare form of bladder tumour
title Inflammatory myofibroblastic tumour: case report of a rare form of bladder tumour
title_full Inflammatory myofibroblastic tumour: case report of a rare form of bladder tumour
title_fullStr Inflammatory myofibroblastic tumour: case report of a rare form of bladder tumour
title_full_unstemmed Inflammatory myofibroblastic tumour: case report of a rare form of bladder tumour
title_short Inflammatory myofibroblastic tumour: case report of a rare form of bladder tumour
title_sort inflammatory myofibroblastic tumour: case report of a rare form of bladder tumour
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8850735/
https://www.ncbi.nlm.nih.gov/pubmed/35158231
http://dx.doi.org/10.1016/j.ijscr.2022.106786
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