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Inflammatory myofibroblastic tumour: case report of a rare form of bladder tumour
INTRODUCTION AND IMPORTANCE: Inflammatory myofibroblastic tumour (IMT) is a rare tumour with malignant potential and has been described in many major organs with the most frequent site being the lungs. However, bladder is an extremely rare location. IMT presents a unique diagnostic challenge because...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8850735/ https://www.ncbi.nlm.nih.gov/pubmed/35158231 http://dx.doi.org/10.1016/j.ijscr.2022.106786 |
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author | Balagobi, Balasingam Gobishangar, Sreekanthan Ginige, Anusha Gamlaksha, Dayal Sanjeyan, Jeyarajah Suvethini, Loganathan |
author_facet | Balagobi, Balasingam Gobishangar, Sreekanthan Ginige, Anusha Gamlaksha, Dayal Sanjeyan, Jeyarajah Suvethini, Loganathan |
author_sort | Balagobi, Balasingam |
collection | PubMed |
description | INTRODUCTION AND IMPORTANCE: Inflammatory myofibroblastic tumour (IMT) is a rare tumour with malignant potential and has been described in many major organs with the most frequent site being the lungs. However, bladder is an extremely rare location. IMT presents a unique diagnostic challenge because of the characteristics it shares with malignant neoplasms. CASE PRESENTATION: Here we report the case of a 47-yearold male who presented with storage lower urinary tract symptoms associated with non-specific lower abdominal pain for one month duration. Contrast-enhanced computed tomography of abdomen and pelvis revealed a 6 cm tumour at the dome and left side anterior wall of the bladder. He underwent laparotomy and partial cystectomy. Histopathology results were consistent with an IMT. CLINICAL DISCUSSION: Even though bladder IMT is indolent in course, typical IMTs can be locally aggressive. Due to the lack of specificity in clinical symptoms, it is not easy to arrive at a precise diagnosis before surgery. Hence, the final diagnosis depends on histomorphological features and the immune histochemical profile. CONCLUSION: It can be challenging to distinguish IMT from malignant neoplasms both clinically and histologically. As such, local surgical resection with close follow-up remains the mainstay of treatment for urinary tract IMT. |
format | Online Article Text |
id | pubmed-8850735 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-88507352022-02-22 Inflammatory myofibroblastic tumour: case report of a rare form of bladder tumour Balagobi, Balasingam Gobishangar, Sreekanthan Ginige, Anusha Gamlaksha, Dayal Sanjeyan, Jeyarajah Suvethini, Loganathan Int J Surg Case Rep Case Report INTRODUCTION AND IMPORTANCE: Inflammatory myofibroblastic tumour (IMT) is a rare tumour with malignant potential and has been described in many major organs with the most frequent site being the lungs. However, bladder is an extremely rare location. IMT presents a unique diagnostic challenge because of the characteristics it shares with malignant neoplasms. CASE PRESENTATION: Here we report the case of a 47-yearold male who presented with storage lower urinary tract symptoms associated with non-specific lower abdominal pain for one month duration. Contrast-enhanced computed tomography of abdomen and pelvis revealed a 6 cm tumour at the dome and left side anterior wall of the bladder. He underwent laparotomy and partial cystectomy. Histopathology results were consistent with an IMT. CLINICAL DISCUSSION: Even though bladder IMT is indolent in course, typical IMTs can be locally aggressive. Due to the lack of specificity in clinical symptoms, it is not easy to arrive at a precise diagnosis before surgery. Hence, the final diagnosis depends on histomorphological features and the immune histochemical profile. CONCLUSION: It can be challenging to distinguish IMT from malignant neoplasms both clinically and histologically. As such, local surgical resection with close follow-up remains the mainstay of treatment for urinary tract IMT. Elsevier 2022-01-24 /pmc/articles/PMC8850735/ /pubmed/35158231 http://dx.doi.org/10.1016/j.ijscr.2022.106786 Text en © 2022 Published by Elsevier Ltd on behalf of IJS Publishing Group Ltd. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Case Report Balagobi, Balasingam Gobishangar, Sreekanthan Ginige, Anusha Gamlaksha, Dayal Sanjeyan, Jeyarajah Suvethini, Loganathan Inflammatory myofibroblastic tumour: case report of a rare form of bladder tumour |
title | Inflammatory myofibroblastic tumour: case report of a rare form of bladder tumour |
title_full | Inflammatory myofibroblastic tumour: case report of a rare form of bladder tumour |
title_fullStr | Inflammatory myofibroblastic tumour: case report of a rare form of bladder tumour |
title_full_unstemmed | Inflammatory myofibroblastic tumour: case report of a rare form of bladder tumour |
title_short | Inflammatory myofibroblastic tumour: case report of a rare form of bladder tumour |
title_sort | inflammatory myofibroblastic tumour: case report of a rare form of bladder tumour |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8850735/ https://www.ncbi.nlm.nih.gov/pubmed/35158231 http://dx.doi.org/10.1016/j.ijscr.2022.106786 |
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