Cargando…

Combining Plant Proteins to Achieve Amino Acid Profiles Adapted to Various Nutritional Objectives—An Exploratory Analysis Using Linear Programming

Although plant proteins are often considered to have less nutritional quality because of their suboptimal amino acid (AA) content, the wide variety of their sources, both conventional and emerging, suggests potential opportunities from complementarity between food sources. This study therefore aimed...

Descripción completa

Detalles Bibliográficos
Autores principales: Dimina, Laurianne, Rémond, Didier, Huneau, Jean-François, Mariotti, François
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8850771/
https://www.ncbi.nlm.nih.gov/pubmed/35187024
http://dx.doi.org/10.3389/fnut.2021.809685
_version_ 1784652671294111744
author Dimina, Laurianne
Rémond, Didier
Huneau, Jean-François
Mariotti, François
author_facet Dimina, Laurianne
Rémond, Didier
Huneau, Jean-François
Mariotti, François
author_sort Dimina, Laurianne
collection PubMed
description Although plant proteins are often considered to have less nutritional quality because of their suboptimal amino acid (AA) content, the wide variety of their sources, both conventional and emerging, suggests potential opportunities from complementarity between food sources. This study therefore aimed to explore whether, and to what extent, combinations of protein ingredients could reproduce an AA profile set as a nutritional objective, and to identify theoretical solutions and limitations. We collected compositional data on protein ingredients and raw plant foods (n = 151), and then ran several series of linear optimization to identify protein ingredient mixes that maximized the content in indispensable AA and reproduced various objective profiles: a “balanced profile,” based on AA requirements for adults; “animal profiles” corresponding to conventional animal protein compositions, and a “cardioprotective profile,” which has been associated with a lower cardiovascular risk. We assumed a very good digestibility of plant protein isolates. As expected, obtaining a balanced profile was obvious, but we also identified numerous plant protein mixtures that met demanding AA profiles. Only for particularly demanding profiles, such as mimicking a particular animal protein, did solutions require the use of protein fractions from more specific sources such as pea or canola. Optimal plant blends could mimic animal proteins such as egg white, cow milk, chicken, whey or casein with a similarity reaching 94.2, 98.8, 86.4, 92.4, and 98.0%, respectively. The limiting constraints were mainly isoleucine, lysine, and histidine target contents. These different solutions offer potential for the formulation of mixtures adapted to specific populations or the design of plant-based substitutes. Some ingredients are not commercially available but they could be developed.
format Online
Article
Text
id pubmed-8850771
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Frontiers Media S.A.
record_format MEDLINE/PubMed
spelling pubmed-88507712022-02-18 Combining Plant Proteins to Achieve Amino Acid Profiles Adapted to Various Nutritional Objectives—An Exploratory Analysis Using Linear Programming Dimina, Laurianne Rémond, Didier Huneau, Jean-François Mariotti, François Front Nutr Nutrition Although plant proteins are often considered to have less nutritional quality because of their suboptimal amino acid (AA) content, the wide variety of their sources, both conventional and emerging, suggests potential opportunities from complementarity between food sources. This study therefore aimed to explore whether, and to what extent, combinations of protein ingredients could reproduce an AA profile set as a nutritional objective, and to identify theoretical solutions and limitations. We collected compositional data on protein ingredients and raw plant foods (n = 151), and then ran several series of linear optimization to identify protein ingredient mixes that maximized the content in indispensable AA and reproduced various objective profiles: a “balanced profile,” based on AA requirements for adults; “animal profiles” corresponding to conventional animal protein compositions, and a “cardioprotective profile,” which has been associated with a lower cardiovascular risk. We assumed a very good digestibility of plant protein isolates. As expected, obtaining a balanced profile was obvious, but we also identified numerous plant protein mixtures that met demanding AA profiles. Only for particularly demanding profiles, such as mimicking a particular animal protein, did solutions require the use of protein fractions from more specific sources such as pea or canola. Optimal plant blends could mimic animal proteins such as egg white, cow milk, chicken, whey or casein with a similarity reaching 94.2, 98.8, 86.4, 92.4, and 98.0%, respectively. The limiting constraints were mainly isoleucine, lysine, and histidine target contents. These different solutions offer potential for the formulation of mixtures adapted to specific populations or the design of plant-based substitutes. Some ingredients are not commercially available but they could be developed. Frontiers Media S.A. 2022-02-03 /pmc/articles/PMC8850771/ /pubmed/35187024 http://dx.doi.org/10.3389/fnut.2021.809685 Text en Copyright © 2022 Dimina, Rémond, Huneau and Mariotti. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Nutrition
Dimina, Laurianne
Rémond, Didier
Huneau, Jean-François
Mariotti, François
Combining Plant Proteins to Achieve Amino Acid Profiles Adapted to Various Nutritional Objectives—An Exploratory Analysis Using Linear Programming
title Combining Plant Proteins to Achieve Amino Acid Profiles Adapted to Various Nutritional Objectives—An Exploratory Analysis Using Linear Programming
title_full Combining Plant Proteins to Achieve Amino Acid Profiles Adapted to Various Nutritional Objectives—An Exploratory Analysis Using Linear Programming
title_fullStr Combining Plant Proteins to Achieve Amino Acid Profiles Adapted to Various Nutritional Objectives—An Exploratory Analysis Using Linear Programming
title_full_unstemmed Combining Plant Proteins to Achieve Amino Acid Profiles Adapted to Various Nutritional Objectives—An Exploratory Analysis Using Linear Programming
title_short Combining Plant Proteins to Achieve Amino Acid Profiles Adapted to Various Nutritional Objectives—An Exploratory Analysis Using Linear Programming
title_sort combining plant proteins to achieve amino acid profiles adapted to various nutritional objectives—an exploratory analysis using linear programming
topic Nutrition
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8850771/
https://www.ncbi.nlm.nih.gov/pubmed/35187024
http://dx.doi.org/10.3389/fnut.2021.809685
work_keys_str_mv AT diminalaurianne combiningplantproteinstoachieveaminoacidprofilesadaptedtovariousnutritionalobjectivesanexploratoryanalysisusinglinearprogramming
AT remonddidier combiningplantproteinstoachieveaminoacidprofilesadaptedtovariousnutritionalobjectivesanexploratoryanalysisusinglinearprogramming
AT huneaujeanfrancois combiningplantproteinstoachieveaminoacidprofilesadaptedtovariousnutritionalobjectivesanexploratoryanalysisusinglinearprogramming
AT mariottifrancois combiningplantproteinstoachieveaminoacidprofilesadaptedtovariousnutritionalobjectivesanexploratoryanalysisusinglinearprogramming