Cargando…

Evaluation of JQ1 Combined With Docetaxel for the Treatment of Prostate Cancer Cells in 2D- and 3D-Culture Systems

Introduction: Prostate cancer (PCa) is dependent on coupled androgen-androgen receptor (AR) signaling for growth and progression. Significant efforts have been made in this research field, as hormonal therapies have greatly improved the survival of patients with metastatic PCa (mPCa). The drug treat...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xu, Yipeng, Pachnikova, Gabriela, Przybilla, Dorothea, Schäfer, Reinhold, Cui, Yingying, Zhou, Dan, Chen, Zihao, Zhao, An, Keilholz, Ulrich
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8850784/ https://www.ncbi.nlm.nih.gov/pubmed/35185589 http://dx.doi.org/10.3389/fphar.2022.839620

Ejemplares similares

IC(50): an unsuitable measure for large-sized prostate cancer spheroids in drug sensitivity evaluation
por: Xu, Yipeng, et al.
Publicado: (2022)

Docetaxel and Doxorubicin Codelivery by Nanocarriers for Synergistic Treatment of Prostate Cancer
por: Li, Ke, et al.
Publicado: (2019)

Itraconazole Reverts ABCB1-Mediated Docetaxel Resistance in Prostate Cancer
por: Lima, Thiago S., et al.
Publicado: (2022)

Beginning JavaScript Charts: with jqPlot, D3, and Highcharts
por: Nelli, Fabio
Publicado: (2013)

Instant jqGrid
por: Manricks, Gabriel
Publicado: (2013)

Abiraterone, Orteronel, Enzalutamide and Docetaxel: Sequential or Combined Therapy?
por: Chen, Ming-kun, et al.
Publicado: (2022)

Effectiveness of Deferred Combined Androgen Blockade Therapy Predicts Efficacy in Abiraterone Acetate Treated Metastatic Castration-Resistant Prostate Cancer Patients after Docetaxel
por: Li, Jian-Ri, et al.
Publicado: (2017)

Geriatric Nutritional Risk Index as a Prognostic Marker for Patients With Metastatic Castration-Resistant Prostate Cancer Receiving Docetaxel
por: Chang, Li-Wen, et al.
Publicado: (2021)

From Chemotherapy to Combined Targeted Therapeutics: In Vitro and in Vivo Models to Decipher Intra-tumor Heterogeneity
por: Gambara, Guido, et al.
Publicado: (2018)

KDM5D predicts response to docetaxel chemotherapy in metastatic castration resistant prostate cancer patients
por: Schäfer, Georg, et al.
Publicado: (2021)

Heterogeneous pathway activation and drug response modelled in colorectal-tumor-derived 3D cultures
por: Schumacher, Dirk, et al.
Publicado: (2019)

Comparison of Systemic Treatments for Metastatic Castration-Resistant Prostate Cancer After Docetaxel Failure: A Systematic Review and Network Meta-analysis
por: Chen, Junru, et al.
Publicado: (2022)

First Line Androgen Deprivation Therapy Duration Is Associated with the Efficacy of Abiraterone Acetate Treated Metastatic Castration-Resistant Prostate Cancer after Docetaxel
por: Li, Jian-Ri, et al.
Publicado: (2017)

Docetaxel-Loaded Nanoparticles Assembled from β-Cyclodextrin/Calixarene Giant Surfactants: Physicochemical Properties and Cytotoxic Effect in Prostate Cancer and Glioblastoma Cells
por: Gallego-Yerga, Laura, et al.
Publicado: (2017)

Identification of Docetaxel as a Potential Drug to Promote HDL Biogenesis
por: Choi, Hong Y., et al.
Publicado: (2021)

Androgen deprivation therapy plus abiraterone or docetaxel as neoadjuvant therapy for very-high-risk prostate cancer: a pooled analysis of two phase II trials
por: Zhuang, Junlong, et al.
Publicado: (2023)

Cost-Effectiveness of Tislelizumab Versus Docetaxel for Previously Treated Advanced Non-Small-Cell Lung Cancer in China
por: Gong, Jinhong, et al.
Publicado: (2022)

Arsenic sulfide combined with JQ1, chemotherapy agents, or celecoxib inhibit gastric and colon cancer cell growth
por: Zhang, Lian, et al.
Publicado: (2015)

Enhanced anti-breast cancer efficacy of co-delivery liposomes of docetaxel and curcumin
por: Ye, Xi, et al.
Publicado: (2022)

BET bromodomain inhibitor (JQ1) and tumor angiogenesis
por: Bid, Hemant Kumar, et al.
Publicado: (2016)

Maslinic Acid Enhances Docetaxel Response in Human Docetaxel-Resistant Triple Negative Breast Carcinoma MDA-MB-231 Cells via Regulating MELK-FoxM1-ABCB1 Signaling Cascade
por: Wang, Ke, et al.
Publicado: (2020)

Characterization of complex structural variation in the CYP2D6-CYP2D7-CYP2D8 gene loci using single-molecule long-read sequencing
por: Turner, Amy J., et al.
Publicado: (2023)

mPEG-PDLLA Micelles Potentiate Docetaxel for Intraperitoneal Chemotherapy in Ovarian Cancer Peritoneal Metastasis
por: Zhang, Yumei, et al.
Publicado: (2022)

Docetaxel-Loaded Novel Nano-Platform for Synergistic Therapy of Non-Small Cell Lung Cancer
por: Feng, Xing, et al.
Publicado: (2022)

Chemotherapeutic properties and side-effects associated with the clinical practice of terpene alkaloids: paclitaxel, docetaxel, and cabazitaxel
por: Sousa-Pimenta, Mário, et al.
Publicado: (2023)

ANO1-downregulation induced by schisandrathera D: a novel therapeutic target for the treatment of prostate and oral cancers
por: Park, SeonJu, et al.
Publicado: (2023)

GLT25D2 Is Critical for Inflammatory Immune Response to Promote Acetaminophen-Induced Hepatotoxicity by Autophagy Pathway
por: Zhang, Xiaohui, et al.
Publicado: (2020)

Machine Learning for Detection of Safety Signals From Spontaneous Reporting System Data: Example of Nivolumab and Docetaxel
por: Bae, Ji-Hwan, et al.
Publicado: (2021)

Corrigendum: Docetaxel-loaded novel nano-platform for synergistic therapy of non-small cell lung cancer
por: Feng, Xing, et al.
Publicado: (2022)

A novel form of docetaxel polymeric micelles demonstrates anti-tumor and ascites-inhibitory activities in animal models as monotherapy or in combination with anti-angiogenic agents
por: Guo, Leilei, et al.
Publicado: (2022)

Working with jqTouch to build websites on top of jQuery
por: David, Matthew
Publicado: (2012)

General mechanism of JQ1 in inhibiting various types of cancer
por: Jiang, Guojuan, et al.
Publicado: (2020)

A Microphysiological Cell-Culturing System for Pharmacokinetic Drug Exposure and High-Resolution Imaging of Arrays of 3D Microtissues
por: Lohasz, Christian, et al.
Publicado: (2021)

Significant Suppression of Non-small-cell Lung Cancer by Hydrophobic Poly(ester amide) Nanoparticles with High Docetaxel Loading
por: Chen, Xing, et al.
Publicado: (2018)

Polydopamine-Functionalized CA-(PCL-ran-PLA) Nanoparticles for Target Delivery of Docetaxel and Chemo-photothermal Therapy of Breast Cancer
por: Kong, Na, et al.
Publicado: (2018)

Shear Speed-Regulated Properties of Long-Acting Docetaxel Control Release Poly (Lactic-Co-Glycolic Acid) Microspheres
por: Zheng, Yuhao, et al.
Publicado: (2020)

Combined Administration of Vitamin D(3) and Geniposide Is Less Effective than Single Use of Vitamin D(3) or Geniposide in the Treatment of Ulcerative Colitis
por: Lu, Yingyu, et al.
Publicado: (2021)

Understanding the role of "sunshine vitamin D" in Parkinson’s disease: A review
por: Behl, Tapan, et al.
Publicado: (2022)

Saikosaponin d Alleviates Liver Fibrosis by Negatively Regulating the ROS/NLRP3 Inflammasome Through Activating the ERβ Pathway
por: Zhang, Kehui, et al.
Publicado: (2022)

Understanding inter-individual variability in pharmacokinetics/pharmacodynamics of aripiprazole in children with tic disorders: Individualized administration based on physiological development and CYP2D6 genotypes
por: Xin, Yingying, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_974khtj2mdhfih4mpj4dvr2bci